1-tert-butylsulfanyl-4,4-dimethyl-pentan-3-one | 92099-24-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-tert-butylsulfanyl-4,4-dimethyl-pentan-3-one
• 英文别名: 1-Tert-butylsulfanyl-4,4-dimethylpentan-3-one
• CAS: 92099-24-6
• 化学式: C₁₁H₂₂OS
• 分子量: 202.361
• InChiKey: JGJXWEODSPQURM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4,4-二甲基-1-戊烯-3-酮 、 叔丁基硫醇 在 吡啶 作用下， 生成 1-tert-butylsulfanyl-4,4-dimethyl-pentan-3-one
  参考文献：
  名称：

  574.有机硫化物的氧化。第十二部分。酮硫醚和酮硫醚对角鲨烯自氧化的抑制作用

  摘要：

  DOI：

  10.1039/jr9620002959

文献信息

• TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS
  申请人：ZHAO Hong

  公开号：US20100233190A1

  公开（公告）日：2010-09-16

  The present invention provides single chain antibody-directed polymeric prodrugs containing multifunctional linkers. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.

  本发明提供了含有多功能连接剂的单链抗体导向的聚合物前药。还揭示了制备聚合物传递系统的方法以及利用这些方法治疗哺乳动物的方法。
• POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES
  申请人：ZHAO Hong

  公开号：US20090202573A1

  公开（公告）日：2009-08-13

  The present invention provides polymeric conjugates containing positively charged moieties. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.
• LYSINE-BASED POLYMERIC LINKERS
  申请人：Zhao Hong

  公开号：US20090203706A1

  公开（公告）日：2009-08-13

  The present invention provides polymeric linkers containing branching moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.
• POLYALKYLENE OXIDES HAVING HINDERED ESTER-BASED BIODEGRADABLE LINKERS
  申请人：ZHAO Hong

  公开号：US20090232833A1

  公开（公告）日：2009-09-17

  The present invention provides polymeric delivery systems including hindered ester moieties. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.
• POLYMERIC LINKERS CONTAINING PYRIDYL DISULFIDE MOIETIES
  申请人：Zhao Hong

  公开号：US20100203066A1

  公开（公告）日：2010-08-12

  The present invention provides polymeric linkers containing pyridyl disulfide moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.