3-Amino-6-(hydroxymethyl)oxane-2,5-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Amino-6-(hydroxymethyl)oxane-2,5-diol
• 化学式: C₆H₁₃NO₄
• 分子量: 163.17
• InChiKey: SNDZDGQLFKEBLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  95.9
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Method of improving hair volume
  申请人：Conopco, Inc.

  公开号：US10813868B2

  公开（公告）日：2020-10-27

  The invention provides a method for improving the volume of hair which comprises the following steps: (i) treating the hair by topical application of a composition comprising from 1 to 25 wt % of one or more glucosamine salts; (ii) shaping the treated hair; (iii) allowing the composition to remain in contact with the shaped hair before drying. Advantageously the method of the invention does not require the breakage of the hair disulfide bonds, does not require the use of high temperature heated implements such as straightening irons, and can be accomplished by a consumer without intervention of a professional hairdresser.

  本发明提供了一种改善发量的方法，包括以下步骤：(i)通过局部使用含有 1 至 25 wt % 的一种或多种葡糖胺盐的组合物来处理头发；(ii)对处理过的头发进行塑形；(iii)在干燥前让组合物与塑形后的头发保持接触。有利的是，本发明的方法不需要破坏头发的二硫键，不需要使用高温加热工具（如直发熨斗），消费者无需专业美发师的干预即可完成。
• Remodeling and glycoconjugation of peptides
  申请人：Novo Nordisk A/S

  公开号：EP2279753B1

  公开（公告）日：2015-09-16
• GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES
  申请人：DeFrees Shawn

  公开号：US20080255040A1

  公开（公告）日：2008-10-16

  The present invention provides sequon polypeptides with an amino acid sequence including one or more exogenous O-linked glycosylation sequence of the invention. In addition, the present invention provides methods of making polypeptide conjugates as well as methods of using such conjugates and their pharmaceutical compositions. The invention further provides libraries of sequon polypeptides, wherein each member of such library includes at least one exogenous O-linked glycosylation sequence of the invention. Also provided are methods of making and using such libraries.
• GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS
  申请人：Novo Nordisk A/S

  公开号：US20150343080A1

  公开（公告）日：2015-12-03

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII
  申请人：Novo Nordisk A/S

  公开号：US20160193353A1

  公开（公告）日：2016-07-07

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.