(hydroxymethyl)-16-crown-5 | 69496-25-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (hydroxymethyl)-16-crown-5
• 英文别名: Hydroxymethyl-16-kronen-5；1,4,7,10,13-Pentaoxacyclohexadec-15-ylmethanol
• CAS: 69496-25-9
• 化学式: C₁₂H₂₄O₆
• 分子量: 264.319
• InChiKey: CSFNJQPQFSZISJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  66.4
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (hydroxymethyl)-16-crown-5 在 盐酸 、 sodium hydroxide 、 potassium hydride 作用下， 以 吡啶 为溶剂， 反应 77.0h， 生成 5-Decyl-2-(1,4,7,10,13-pentaoxacyclohexadec-15-ylmethoxy)benzoic acid
  参考文献：
  名称：

  Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471

  摘要：

  DOI：
• 作为产物：
  描述：

  15-methylene-1,4,7,10,13-pentaoxacyclohexadecane 以88%的产率得到
  参考文献：
  名称：

  TOMOI M.; ABE O.; IKEDA M.; KIHARA K.; KAKINCHI H., TETRAHEDRON LETT., 1978, NO 33, 3031-3034

  摘要：

  DOI：

文献信息

• Molecular design of crown ethers. 4. Syntheses and selective cation binding of 16-crown-5 and 19-crown-6 lariats
  作者：Mikio Ouchi、Yoshihisa Inoue、Kazuhito Wada、Shinichi Iketani、Tadao Hakushi、Edwin Weber

  DOI：10.1021/jo00388a016

  日期：1987.6
• Ring Size Effect of Crown Ether on the Fixation of Carbon Dioxide into an Oxirane Polymer
  作者：Shin-ichi Yamamoto、Osamu Moriya、Takeshi Endo

  DOI：10.1021/ma040131a

  日期：2005.3.1

  Several methacrylate derivatives having a crown ether group, the size of which was changed from 12-crown-4 to 16-crown-5, were newly prepared and copolymerized with glycidyl methacrylate under radical conditions. The obtained copolymers (CP1-5) were employed for the fixation of CO2 into the oxirane moieties using lithium salt as a catalyst. The conversion of oxirane to five-membered cyclic carbonate groups by fixation of CO2 was related with the ring size of crown ethers and reflected the association constants for Li+. The most efficient fixation of CO2 in nitromethane solution was observed in the use of CP3, having 14-crown-4 groups, in which oxirane groups were transformed into the corresponding cyclic carbonate groups quantitatively, and further, the reaction proceeded readily even in the solid state.
• Dodecylphosphoric Acid-Armed Crown Ethers: Specific Complexing Abilities toward Alkali Metal Cations
  作者：Yoichi Habata、Harumi Ugajin、Sadatoshi Akabori

  DOI：10.1021/jo00082a033

  日期：1994.2
• Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471
  作者：Czech, Bronislaw P.、Czech, Anna、Son, Byungki、Lee, Han Koo、Bartsch, Richard A.

  DOI：——

  日期：——
• TOMOI M.; ABE O.; IKEDA M.; KIHARA K.; KAKINCHI H., TETRAHEDRON LETT., 1978, NO 33, 3031-3034
  作者：TOMOI M.、 ABE O.、 IKEDA M.、 KIHARA K.、 KAKINCHI H.

  DOI：——

  日期：——