Hexane-1,6-diyl bis(4-methoxybenzoate) | 390359-18-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Hexane-1,6-diyl bis(4-methoxybenzoate)
• 英文别名: 6-(4-methoxybenzoyl)oxyhexyl 4-methoxybenzoate
• CAS: 390359-18-9
• 化学式: C₂₂H₂₆O₆
• 分子量: 386.445
• InChiKey: ZALQHEOANJAMNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  28
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3-iodopropyl 4-methoxybenzoate 在 nickel(II) iodide 、 2-(4,5-二氢-1H-咪唑-2-基)-吡啶 、 lithium methanolate 、 联硼酸频那醇酯 作用下， 以 N-甲基吡咯烷酮 为溶剂， 反应 16.0h， 以70%的产率得到Hexane-1,6-diyl bis(4-methoxybenzoate)
  参考文献：
  名称：

  Nickel-catalyzed cross-coupling of unactivated alkyl halides using bis(pinacolato)diboron as reductant

  摘要：

  使用双（匹卡洛酸酯）二硼作为末端还原剂，可以高效催化非活化的次级和一级卤烃进行镍催化偶联反应，生成良产率的C(sp3)–C(sp3)偶联产物。这种温和的催化条件表现出优异的官能团耐受性，以及良好的化学选择性，仅需1.5当量的一级溴化物与次级溴化物进行偶联。初步的机理研究表明，体内有机硼/铃木反应的可能性不大。研究发现，碱和配体对选择这一还原偶联路径有更深远的影响。良好的化学选择性似乎是由于Ni–Bpin催化中间体的形成，这要求卤烃偶联伙伴之间的尺寸和反应性匹配，以实现最佳偶联效率。

  DOI：

  10.1039/c3sc51098k

文献信息

• Solvent-free synthesis of symmetric methylene diesters <i>via</i> direct reaction of aromatic carboxylates with 1,<i>n</i>-dihaloalkanes
  作者：Lin Bai、Shenglong Ding、Xiaofang Ma

  DOI：10.1039/d1ra04814g

  日期：——

  An efficient methodology for the synthesis of symmetrical methylene diesters was developed through direct reaction of various aromatic carboxylates with 1,n-dihaloalkanes under solvent-free conditions. This strategy offers a high product yield, facile work-up and purification, and an environmentally friendly approach to obtain long-chain methylene carboxylate scaffolds with increased diversity.

  通过各种芳族羧酸盐与 1, n-二卤代烷烃在无溶剂条件下的直接反应，开发了一种合成对称亚甲基二酯的有效方法。该策略提供了高产率、简便的后处理和纯化，以及一种环境友好的方法来获得具有增加多样性的长链羧酸亚甲酯支架。
• SOLID INK COMPOSITIONS COMPRISING AMORPHOUS ESTERS OF CITRIC ACID
  申请人：Morimitsu Kentaro

  公开号：US20120272861A1

  公开（公告）日：2012-11-01

  A solid ink composition comprising an amorphous component, a crystalline material, and optionally, a colorant, which are suitable for ink jet printing, including printing on coated paper substrates. In embodiments, the amorphous component is synthesized from an esterification reaction of citric acid.
• Phase Separation Ink
  申请人：Odell Peter G.

  公开号：US20120274713A1

  公开（公告）日：2012-11-01

  A phase separation ink including at least one crystallizable component that crystallizes as it cools from a first ink jetting temperature to a second lower temperature; at least one amorphous component comprising a material that remains amorphous at the second temperature; an optional colorant; wherein the at least one crystallizable component and the at least one amorphous component are in a molten, single phase state at the first ink jetting temperature; wherein at the second temperature, the phase separation ink comprises a crystalline phase comprising the at least one crystallizable component and an amorphous phase comprising the at least one amorphous component; wherein the amorphous phase of the at least one phase separation ink substantially penetrates into the final image receiving substrate and the crystalline phase of the at least one phase separation ink substantially remains on the surface of the final image receiving substrate.
• HOT MELT INK COMPOSITION, METHOD FOR PREPARING A HOT MELT INK COMPOSITION AND USE OF A HOT MELT INK COMPOSITION
  申请人：OCE-TECHNOLOGIES B.V.

  公开号：US20150124030A1

  公开（公告）日：2015-05-07

  The invention relates to a hot melt ink composition, the hot melt ink composition being solid at room temperature and in a liquid state at an elevated temperature, comprising a binder, a colorant, a crystalline material, and a crystallization retardant, wherein the crystalline material is a di-substituted compound and the crystallization retardant is a mono-substituted derivative of the crystalline material. The invention further relates to a method for preparing such hot melt compositions and to use of a hot melt ink composition.
• US8287632B1
  申请人：——

  公开号：US8287632B1

  公开（公告）日：2012-10-16