morpholinium trifluoromethanesulfonate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: morpholinium trifluoromethanesulfonate
• 英文别名: morpholinium triflate；Morpholine trifluoromethanesulfonate；morpholine;trifluoromethanesulfonic acid
• 化学式: CHF₃O₃S*C₄H₉NO
• 分子量: 237.2
• InChiKey: OVXDLDSWRLLUJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.37
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  91.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  吗啉 、 三氟甲磺酸酐 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 1-(trifluoromethanesulfonyl)morpholine 、 morpholinium trifluoromethanesulfonate
  参考文献：
  名称：

  Triflamides and Triflates of Six-membered Heterocyclic Amines

  摘要：

  Reactions of secondary cyclic amines (piperidine, morpholine, thiomorpholine, 1lambda(6), 4-thiazinane-1,1-dione) with trifluoromethanesulfonic anhydride or with N-phenyltriflimide both in the presence and in the absence of a base (Et3N) result in formation of corresponding triflamides and triflates of the initial amines. The triflates and triflamides can be distinguished by their F-19 and N-15 NMR spectra and the presence in the IR spectra of salts of absorption bands in the region 3270-3000 cm(-1) lacking in the spectra of triflamides.

  DOI：

  10.1023/b:rujo.0000010190.79187.b9
• 作为试剂：
  描述：

  (1R)-cis-2,2-dimethyl-3-(2-chloro-2-acetylvinyl)cyclopropanecarboxylic acid methyl ester 在 morpholinium trifluoromethanesulfonate 作用下， 反应 20.0h， 以79%的产率得到methyl (1R)-cis-2,2-dimethyl-3-(2-chloro-3,3-difluoro-1-butenyl)cyclopropanecarboxylate
  参考文献：
  名称：

  Fokin, A. A.; Butova, E. D.; Kolomitsin, I. V., Russian Journal of Organic Chemistry, 1994, vol. 30, # 5.1, p. 710 - 720

  摘要：

  DOI：

文献信息

• Triflamides and Triflates of Six-membered Heterocyclic Amines
  作者：B. A. Shainyan、L. L. Tolstikov、A. R. Zhinkin

  DOI：10.1023/b:rujo.0000010190.79187.b9

  日期：2003.8

  Reactions of secondary cyclic amines (piperidine, morpholine, thiomorpholine, 1lambda(6), 4-thiazinane-1,1-dione) with trifluoromethanesulfonic anhydride or with N-phenyltriflimide both in the presence and in the absence of a base (Et3N) result in formation of corresponding triflamides and triflates of the initial amines. The triflates and triflamides can be distinguished by their F-19 and N-15 NMR spectra and the presence in the IR spectra of salts of absorption bands in the region 3270-3000 cm(-1) lacking in the spectra of triflamides.