N-(6-乙基吡啶-2-基)苯甲酰胺 | 686290-03-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-(6-乙基吡啶-2-基)苯甲酰胺
• 英文名称: N-(6-ethyl-2-pyridyl)benzamide
• 英文别名: N-(6-Ethylpyridin-2-yl)benzamide
• CAS: 686290-03-9
• 化学式: C₁₄H₁₄N₂O
• 分子量: 226.278
• InChiKey: XXJUFMCTUBXHHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  dibromo(1,2-dimethoxyethane)nickel(II) 、 N-(6-乙基吡啶-2-基)苯甲酰胺 以 四氢呋喃 为溶剂， 以72%的产率得到[N-(6-ethyl-2-pyridyl)benzamide]dinickel(II) di-μ-bromide dibromide
  参考文献：
  名称：

  Synthesis and characterization of N-(2-pyridyl)benzamide-based nickel complexes and their activity for ethylene oligomerization

  摘要：

  A series of N-(2-pyridyl)benzamides (1)-(11) and their nickel complexes, [N-(2-pyridyl)benzamide]dinickel(II) di-mu-bromide dibromide (12)-(16) and (aryl)[N-(2-pyridyl)benzamido](triphenylphosphine)nickel(II) (17)-(24), were synthesized and characterized. The single-crystal X-ray analysis revealed that 12 and 14 are binuclear nickel complexes bridged by bromine atoms and each nickel atom adopts a distorted trigonal bipyramidal geometry. The key feature of the complexes 17, 19 and 23 is each has a six-membered nickel chelate ring including a deprotonated secondary nitrogen atom and an O-donor atom. The nickel complexes show moderate to high catalytic activity for ethylene oligomerization with methylaluminoxane (MAO) as cocatalyst. The activity of 12-16/MAO systems is up to 3.3 x 10(4) g mol(-1) h(-1) whereas for 17-24/MAO systems it is up to 4.94 x 10(5) g mol(-1) atm(-1) h(-1). The influence of Al/Ni molar ratio, reaction temperature, reaction period and PPh3/Ni molar ratio on catalytic activity was investigated. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2003.12.022
• 作为产物：
  描述：

  2-氨基-6-乙基吡啶 、 苯甲酰氯 以 四氢呋喃 、 吡啶 为溶剂， 反应 12.0h， 以78%的产率得到N-(6-乙基吡啶-2-基)苯甲酰胺
  参考文献：
  名称：

  Synthesis and characterization of N-(2-pyridyl)benzamide-based nickel complexes and their activity for ethylene oligomerization

  摘要：

  A series of N-(2-pyridyl)benzamides (1)-(11) and their nickel complexes, [N-(2-pyridyl)benzamide]dinickel(II) di-mu-bromide dibromide (12)-(16) and (aryl)[N-(2-pyridyl)benzamido](triphenylphosphine)nickel(II) (17)-(24), were synthesized and characterized. The single-crystal X-ray analysis revealed that 12 and 14 are binuclear nickel complexes bridged by bromine atoms and each nickel atom adopts a distorted trigonal bipyramidal geometry. The key feature of the complexes 17, 19 and 23 is each has a six-membered nickel chelate ring including a deprotonated secondary nitrogen atom and an O-donor atom. The nickel complexes show moderate to high catalytic activity for ethylene oligomerization with methylaluminoxane (MAO) as cocatalyst. The activity of 12-16/MAO systems is up to 3.3 x 10(4) g mol(-1) h(-1) whereas for 17-24/MAO systems it is up to 4.94 x 10(5) g mol(-1) atm(-1) h(-1). The influence of Al/Ni molar ratio, reaction temperature, reaction period and PPh3/Ni molar ratio on catalytic activity was investigated. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2003.12.022

文献信息

• Fungicide hydroximoyl-tetrazole derivatives
  申请人：Christian Isabelle

  公开号：US20090291969A1

  公开（公告）日：2009-11-26

  The present invention relates to hydroximoyl-tetrazole derivatives of formula (I) wherein T represent a tetrazolyl substituent, A represents a carbo- or heterocycle, L 1 and L 2 represent various linking groups and Q represents a 5-membered heterocycle, their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.

  本发明涉及公式（I）的羟肟基四唑衍生物，其中T代表四唑基取代基，A代表碳或杂环，L1和L2代表不同的连接基，Q代表5元杂环，其制备方法，其作为杀真菌活性剂的用途，特别是作为杀真菌组合物的形式，以及使用这些化合物或组合物控制植物病原真菌，尤其是植物的方法。
• US8119645B2
  申请人：——

  公开号：US8119645B2

  公开（公告）日：2012-02-21
• Synthesis and characterization of N-(2-pyridyl)benzamide-based nickel complexes and their activity for ethylene oligomerization
  作者：Wen-Hua Sun、Wen Zhang、Tielong Gao、Xiubo Tang、Liyi Chen、Yan Li、Xianglin Jin

  DOI：10.1016/j.jorganchem.2003.12.022

  日期：2004.3

  A series of N-(2-pyridyl)benzamides (1)-(11) and their nickel complexes, [N-(2-pyridyl)benzamide]dinickel(II) di-mu-bromide dibromide (12)-(16) and (aryl)[N-(2-pyridyl)benzamido](triphenylphosphine)nickel(II) (17)-(24), were synthesized and characterized. The single-crystal X-ray analysis revealed that 12 and 14 are binuclear nickel complexes bridged by bromine atoms and each nickel atom adopts a distorted trigonal bipyramidal geometry. The key feature of the complexes 17, 19 and 23 is each has a six-membered nickel chelate ring including a deprotonated secondary nitrogen atom and an O-donor atom. The nickel complexes show moderate to high catalytic activity for ethylene oligomerization with methylaluminoxane (MAO) as cocatalyst. The activity of 12-16/MAO systems is up to 3.3 x 10(4) g mol(-1) h(-1) whereas for 17-24/MAO systems it is up to 4.94 x 10(5) g mol(-1) atm(-1) h(-1). The influence of Al/Ni molar ratio, reaction temperature, reaction period and PPh3/Ni molar ratio on catalytic activity was investigated. (C) 2004 Elsevier B.V. All rights reserved.