benzyl 2,4-dibenzoyl-α-L-fucoside | 1243247-59-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: benzyl 2,4-dibenzoyl-α-L-fucoside
• 英文别名: [(2S,3S,4R,5S,6R)-5-benzoyloxy-4-hydroxy-2-methyl-6-phenylmethoxyoxan-3-yl] benzoate
• CAS: 1243247-59-7
• 化学式: C₂₇H₂₆O₇
• 分子量: 462.499
• InChiKey: RJFFKXUUZDYYPH-IGAPMBCYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  91.3
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  benzyl 2,4-dibenzoyl-α-L-fucoside 、 [(2R,3S,4S,5R,6R)-3-benzoyloxy-4,5-bis(naphthalen-2-ylmethoxy)-6-(2,2,2-trichloroethanimidoyl)oxyoxan-2-yl]methyl benzoate 在 三氟甲磺酸三甲基硅酯 作用下， 以 二氯甲烷 为溶剂， 以88%的产率得到[(2R,3S,4S,5R,6R)-3-benzoyloxy-6-[(2S,3R,4R,5S,6R)-3,5-dibenzoyloxy-2-methyl-6-phenylmethoxyoxan-4-yl]oxy-4,5-bis(naphthalen-2-ylmethoxy)oxan-2-yl]methyl benzoate
  参考文献：
  名称：

  Novel galactosyl donor with 2-naphthylmethyl (NAP) as the non-participating group at C-2 position: efficient synthesis of α-galactosyl ceramide

  摘要：

  Piedommant alpha-linked products can be generated in glycosylation involving galactosyl trichloroacetimiclate donors with 2-naphthylmethyl (NAP)as the non-participating group at C-2 position The above-mentioned donor was successfully utilized for the synthesis of alpha-galactosyl ceiamide. (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetlet.2010.06.071

文献信息

• Novel galactosyl donor with 2-naphthylmethyl (NAP) as the non-participating group at C-2 position: efficient synthesis of α-galactosyl ceramide
  作者：Sirajud D. Khaja、Vipin Kumar、Misbah Ahmad、Jun Xue、Khushi L. Matta

  DOI：10.1016/j.tetlet.2010.06.071

  日期：2010.8

  Piedommant alpha-linked products can be generated in glycosylation involving galactosyl trichloroacetimiclate donors with 2-naphthylmethyl (NAP)as the non-participating group at C-2 position The above-mentioned donor was successfully utilized for the synthesis of alpha-galactosyl ceiamide. (C) 2010 Elsevier Ltd All rights reserved