N-(9-芴甲氧羰基)-GAMMA-羧基-D-谷氨酸GAMMA-二叔丁酯 | 111662-65-8

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 谷氨酸类衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: N-(9-芴甲氧羰基)-GAMMA-羧基-D-谷氨酸GAMMA-二叔丁酯
• 中文别名: N-(9-芴甲氧羰基)-GAMMA-羧基-D-谷氨酸 GAMMA-二叔丁酯
• 英文名称: Fmoc-D-Gla(otbu)2-OH
• 英文别名: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-4-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopentanoic acid
• CAS: 111662-65-8
• 化学式: C₂₉H₃₅NO₈
• 分子量: 525.6
• InChiKey: XJRUHYXXHXECDI-HSZRJFAPSA-N

物化性质

• 沸点：
  695.3±55.0 °C(Predicted)
• 密度：
  1.217±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  38
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  128
• 氢给体数：
  2
• 氢受体数：
  8

安全信息

• 危险等级：
  IRRITANT

文献信息

• BIOPROBES AND METHODS OF USE THEREOF
  申请人：Kelley Shana O.

  公开号：US20140087375A1

  公开（公告）日：2014-03-27

  Disclosed are biomolecule based bioprobes that exhibit improved water solubility and monolayer-forming properties with substantially little or no aggregation that can appreciably interfere with binding of the bioprobes to a target nucleotide. The bioprobes may be used in conjunction with a suitable reporter system to detect very small quantities of biological markers. The bio-probes comprise a nucleobase sequence capable of hybridizing to a target nucleotide; and at least one charged functional group attached to said nucleobase sequence. Also disclosed are biosensors, and sensing devices that comprise the bio-probe. Further disclosed are suitable electrochemical reporter systems for use with bioprobes. Methods of use of these devices and probes, including for the detection of target biomarkers, including biomarkers for cancer cells or pathogens, are also included.
• US9335289B2
  申请人：——

  公开号：US9335289B2

  公开（公告）日：2016-05-10
• US9816129B2
  申请人：——

  公开号：US9816129B2

  公开（公告）日：2017-11-14