3,3-Dimethylbutane-1,1-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,3-Dimethylbutane-1,1-diol
• 化学式: C₆H₁₄O₂
• 分子量: 118.17
• InChiKey: QUJATIZORFBTII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES
  申请人：Portland State University

  公开号：US20160223558A1

  公开（公告）日：2016-08-04

  Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R 1 /R 2 , R 2 /R 3 , R 3 /R 4 , R 5 /R 6 , R 6 /R 7 , and/or R 7 /R 8 together form a substituted or unsubstituted cycloalkyl or aryl.

  公开了用于选择性检测分析物的化合物实施例，以及使用这些化合物检测分析物的方法和试剂盒。这些化合物是包括至少一种荧光团的桥联紫罗兰类化合物，其一般结构如下：至少有R1/R2、R2/R3、R3/R4、R5/R6、R6/R7和/或R7/R8中的至少一对形成取代或未取代的环烷基或芳基。
• THIOL DETECTION
  申请人：Strongin Robert Michael

  公开号：US20120276649A1

  公开（公告）日：2012-11-01

  Embodiments of compounds for selectively detecting a thiol are disclosed. In some embodiments, the compounds are bridged viologens, and the compounds are capable of reacting with homocysteine and/or glutathione in a buffered solution to produce a change in the solution's absorbance spectrum and/or emission spectrum. Also disclosed are embodiments of methods and kits for detecting homocysteine and/or glutathione with the disclosed bridged viologens.

  本发明揭示了用于选择性检测巯基的化合物实施例。在某些实施例中，这些化合物是桥联苯并咪唑化合物，它们能够与缓冲溶液中的同型半胱氨酸和/或谷胱甘肽发生反应，产生溶液吸收光谱和/或发射光谱的变化。本发明还揭示了使用上述桥联苯并咪唑化合物检测同型半胱氨酸和/或谷胱甘肽的方法和试剂盒实施例。
• Stabilizer composition and use thereof
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0861847A2

  公开（公告）日：1998-09-02

  A stabilizer composition which manifests an improved effect against thermal degradation and oxidation degradation of an organic material comprises a phosphite of formula (I) wherein R1, R2, R4 and R5 each independently represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group having 5 to 8 carbon atoms, an alkylcycloalkyl group having 6 to 12 carbon atoms, an aralkyl group having 7 to 12 carbon atoms or a phenyl group, R3 and R6 each independently represent a hydrogen atom or an alkyl group having 1 to 8 carbon atoms, X1 represents a divalent alcohol residue, X2 represents a direct bond or an alkylene group having 1 to 8 carbon atoms, and Y represents a hydroxyl group, and an amine (A).

  一种可改善有机材料热降解和氧化降解效果的稳定剂组合物包括式（I）的亚磷酸酯 其中 R1、R2、R4 和 R5 各自独立地代表氢原子、具有 1 至 8 个碳原子的烷基、具有 5 至 8 个碳原子的环烷基、具有 6 至 12 个碳原子的烷基环烷基、具有 7 至 12 个碳原子的芳烷基或苯基、R3 和 R6 各自独立地代表氢原子或具有 1 至 8 个碳原子的烷基，X1 代表二价醇残基，X2 代表直接键或具有 1 至 8 个碳原子的亚烷基，Y 代表羟基和胺 (A)。
• Piperidinyl derivatives as modulators of chemokine receptor activity
  申请人：Bristol-Myers Squibb Company

  公开号：EP2471773A1

  公开（公告）日：2012-07-04

  The present application describes substituted piperidinyl modulators of MIP-1α or CCR-1 or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using said modulators are disclosed.

  本申请介绍了 MIP-1α 或 CCR-1 的取代哌啶基调节剂或其立体异构体或药学上可接受的盐类。此外，还公开了使用上述调节剂治疗和预防炎症性疾病（如哮喘和过敏性疾病）以及自身免疫性病症（如类风湿性关节炎和移植排斥反应）的方法。
• Phosphites and their production and use
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0767175B1

  公开（公告）日：2001-12-12