(2S,3R,4S,5S,6R)-6-Hydroxymethyl-3-octyloxy-tetrahydro-pyran-2,4,5-triol | 142025-73-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5S,6R)-6-Hydroxymethyl-3-octyloxy-tetrahydro-pyran-2,4,5-triol
• 英文别名: (2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3-octoxyoxane-2,4,5-triol
• CAS: 142025-73-8
• 化学式: C₁₄H₂₈O₆
• 分子量: 292.373
• InChiKey: BVHPDIWLWHHJPD-RGDJUOJXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Methods and compositions for gene delivery
  申请人：——

  公开号：US20030134420A1

  公开（公告）日：2003-07-17

  The present invention provides novel compositions and formulations for delivering anionic compounds, particularly polynucleotides (DNA and RNA), across cellular boundaries (e.g., cellular membranes) either in vivo or in vitro.

  本发明提供了用于递送阴离子化合物的新型组合物和配方，特别是多核苷酸（DNA和RNA），跨越细胞边界（例如细胞膜）的方法，无论是在体内还是体外。
• Regulators of the hedgehog pathway, compositions and uses related thereto
  申请人：Beachy A. Philip

  公开号：US20060128639A1

  公开（公告）日：2006-06-15

  The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.

  本发明提供了调节平滑蛋白依赖性通路激活的方法和试剂等。在某些实施例中，这些方法可用于对抗由于刺猬增强功能、ptc失去功能或平滑蛋白增强功能突变引起的刺猬通路不必要激活的表型效应。
• TRIPODAL CYCLOHEXANE DERIVATIVES AND THEIR USE AS CARBOHYDRATE RECEPTORS
  申请人：Miller Benjamin L.

  公开号：US20100041568A1

  公开（公告）日：2010-02-18

  A tri-podal compound according to formula (I) wherein, each Z is the same and is a substituted or unsubstituted N-heteroaromatic single-, multiple-, or fused-ring; and each A is the same, and can represent a direct bond between the cyclohexane ring and Z, or a carboxamide group (—C(O)—N(H)—). Use of the compounds in combinatorial libraries, methods of making the tripodal compounds, sensor devices for detecting carbohydrate targets, and methods of using the tripodal compounds to detect carbohydrate targets in a sample are also disclosed.

  一种三脚架化合物，其化学式为（I），其中每个Z相同且是取代或未取代的N-杂环芳香单环、多环或融合环；每个A相同，可以表示环己烷环和Z之间的直接键或羧酰胺基团（-C（O）-N（H）-）。本文还披露了在组合化学库中使用该化合物、制备三脚架化合物的方法、用于检测碳水化合物靶标的传感器装置以及使用三脚架化合物在样品中检测碳水化合物靶标的方法。
• Hot melt ink compositions
  申请人：XEROX CORPORATION

  公开号：EP0404493A2

  公开（公告）日：1990-12-27

  Disclosed are hot melt ink compositions suitable for ink jet printing which comprise a colorant, a binder, and a propellant selected from the group consisting of hydrazine; cyclic amines; ureas; carboxylic acids; sulfonic acids; aldehydes; ketones; hydrocarbons; esters; phenols; amides; imides; halocarbons; urethanes; ethers; sulfones; sulfamides; sulfonamides; phosphites; phosphonates; phosphates; alkyl sulfides; alkyl acetates; and sulfur dioxide. Also disclosed are hot melt ink compositions suitable for ink jet printing which comprise a colorant, a propellant, and a binder selected from the group consisting of rosin esters; polyamides; dimer acid amides; fatty acid amides; epoxy resins; fluid paraffin waxes; fluid microcrystalline waxes; Fischer-Tropsch waxes; polyvinyl alcohol resins; polyols; cellulose esters; cellulose ethers; polyvinyl pyridine resins; fatty acids; fatty acid esters; poly sulfonamides; benzoate esters; long chain alcohols; phthalate plasticizers; citrate plasticizers; maleate plasticizers; sulfones; polyvinyl pyrrolidinone copolymers; polyvinyl pyrrolidone/polyvinyl acetate copolymers; novalac resins; natural product waxes; mixtures of linear primary alcohols and linear long chain amides; and mixtures of linear primary alcohols and fatty acid amides. Also disclosed are hot melt ink compositions which comprise a colorant, a propellant and a binder, wherein the binder comprises a liquid crystalline material.

  本发明公开了适用于喷墨印刷的热熔油墨组合物，该组合物包含着色剂、粘合剂和推进剂，推进剂选自以下组别：肼；环胺；脲；羧酸；磺酸；醛；酮；烃；酯；酚；酰胺；酰亚胺；卤化碳；氨基甲酸乙酯；醚；砜；酰胺；磺酰胺；亚磷酸盐；膦酸盐；磷酸盐；烷基硫化物；乙酸烷基酯；以及二氧化硫。还公开了适用于喷墨印刷的热熔油墨组合物，该组合物包含着色剂、推进剂和粘合剂，这些粘合剂选自松香酯；聚酰胺；二聚酸酰胺；脂肪酸酰胺；环氧树脂；流体石蜡；流体微晶蜡；费托蜡；聚乙烯醇树脂；多元醇；纤维素酯；纤维素醚；聚乙烯吡啶树脂；脂肪酸；脂肪酸酯；聚磺酰胺；苯甲酸酯；长链醇；邻苯二甲酸酯增塑剂；柠檬酸酯增塑剂；马来酸酯增塑剂；砜；聚乙烯吡咯烷酮共聚物；聚乙烯吡咯烷酮/聚醋酸乙烯酯共聚物；novalac 树脂；天然产品蜡；线性伯醇和线性长链酰胺的混合物；以及线性伯醇和脂肪酸酰胺的混合物。还公开了热熔油墨组合物，它包括着色剂、推进剂和粘结剂，其中粘结剂包括液晶材料。
• Liquid crystal display device
  申请人：HOECHST AKTIENGESELLSCHAFT

  公开号：EP0690334A2

  公开（公告）日：1996-01-03

  To provide a liquid crystal display device provided with a liquid crystal alignment layer which is excellent in adhesion to a glass substrate and which has less dependency of display characteristics upon a viewing angle. A liquid crystal display device having a liquid crystal layer between a pair of substrates each comprising a transparent electrode having provided thereon an alignment layer wherein the alignment layers are arranged inside so as to face each other, characterized in that a mixture of a polyamide (A) containing siloxane component as a constituting unit and a polymer (B) having a property of aligning the liquid crystal in such a manner that the direction of a long axis of the liquid crystal molecule projected on the surface of the substrate is different from a rubbing direction is used as an alignment layer material of at least one of the facing surfaces on the pair of substrates.

  提供一种液晶显示装置，其液晶对位层与玻璃基板的附着力极佳，且显示特性对视角的依赖性较小。 一种液晶显示装置，在一对基板之间有一个液晶层，每个基板包括一个透明电极，在透明电极上有一个配向层，配向层排列在内部，彼此面对、其特征在于，由含有硅氧烷成分的聚酰胺（A）作为构成单元和一种聚合物（B）组成的混合物被用作这对基板上至少一个面对面的对准层材料，这种聚合物（B）具有使液晶分子在基板表面上投射的长轴方向与摩擦方向不同的对准液晶的特性。