1-(1-Ethoxy-ethoxy)-2-methoxy-ethane | 81616-95-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(1-Ethoxy-ethoxy)-2-methoxy-ethane
• 英文别名: 1-Ethoxy-1-(2-methoxyethoxy)ethane
• CAS: 81616-95-7
• 化学式: C₇H₁₆O₃
• 分子量: 148.202
• InChiKey: GINQMDNORSUABQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  烯丙基三甲基硅烷 、 1-(1-Ethoxy-ethoxy)-2-methoxy-ethane 在 四氯化钛 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以86%的产率得到4-ethoxy-1-pentene
  参考文献：
  名称：

  Reaction of 2-methoxyethyl acetals with allylsilanes in the presence of titanium tetrachloride: regioselective carbon-oxygen bond cleavage of the unsymmetrical acetals

  摘要：

  DOI：

  10.1021/jo00133a058

文献信息

• [EN] COMPOUNDS THAT INHIBIT MCL-1 PROTEIN<br/>[FR] COMPOSÉS INHIBANT LA PROTÉINE MCL-1
  申请人：AMGEN INC

  公开号：WO2017147410A1

  公开（公告）日：2017-08-31

  Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.

  本文提供了髓样细胞白血病1蛋白（Mcl-1）抑制剂，其制备方法，相关的药物组合物，以及使用这些物质的方法。例如，本文提供了化合物I的公式，及其药用盐和含有这些化合物的药物组合物。本文提供的化合物和组合物可以用于治疗癌症等疾病或症状。
• LUBRICATING OIL COMPOSITION FOR REFRIGERATORS
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2083062A1

  公开（公告）日：2009-07-29

  Provided is a lubricating oil composition for a refrigerator which uses a base oil including as the main component at least one kind of oxygen-containing compounds selected from polyoxyalkylene glycols, polyvinyl ethers, copolymers of poly(oxy)alkylene glycols or monoethers thereof and polyvinyl ethers, polyol esters, and polycarbonates. The lubricating oil composition for a refrigerator is used for a refrigerator that uses, as a refrigerant, a fluorine-containing organic compound, which is a refrigerant applicable to current car air conditioner systems or the like and has a specific polar structure, and has favorable sealing property, a low coefficient of friction factor in a sliding part, and excellent stability as well as excellent compatibility with the refrigerant.

  本发明提供了一种用于冰箱的润滑油组合物，其使用的基础油包括至少一种作为主要成分的含氧化合物，这些含氧化合物选自聚氧烷基乙二醇、聚乙烯醚、聚（氧）烷基乙二醇的共聚物或其单醚以及聚乙烯醚、多元醇酯和聚碳酸酯。冰箱润滑油组合物用于使用含氟有机化合物作为制冷剂的冰箱，该制冷剂是一种适用于当前汽车空调系统或类似系统的制冷剂，具有特定的极性结构，并具有良好的密封性能、滑动部件摩擦系数低、稳定性极佳以及与制冷剂的兼容性极佳。
• LUBRICANT OIL COMPOSITION FOR COMPRESSION REFRIGERATOR
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2623583A1

  公开（公告）日：2013-08-07

  It is to provide a lubricating oil composition for a compression refrigerator, which is excellent in the thermal/chemical stability even when used in a compression refrigerator that uses a saturated fluorinated hydrocarbon refrigerant having a lower global warming potential and a fewer carbon atoms, by including in a base oil an organic compound having a double bond in a molecule, which is at least one kind selected from an organic compound having at least two non-conjugated double bonds in the molecule, a terpene compound having a double bond in the molecule, and C12 to C30 aliphatic unsaturated hydrocarbon having one double bond in the molecule.

  本发明旨在提供一种用于压缩式制冷机的润滑油组合物，该组合物即使用于使用全球变暖潜能值较低且碳原子数较少的饱和含氟碳氢化合物制冷剂的压缩式制冷机中，也具有优异的热稳定性/化学稳定性、在基础油中加入分子中含有双键的有机化合物，该双键至少选自分子中含有至少两个非共轭双键的有机化合物、分子中含有一个双键的萜烯化合物和分子中含有一个双键的 C12 至 C30 脂肪族不饱和烃中的一种。
• Lubricating oil composition for refrigerators
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：US10358590B2

  公开（公告）日：2019-07-23

  Provided is a lubricating oil composition for a refrigerator which uses a base oil including as the main component at least one kind of oxygen-containing compounds selected from polyoxyalkylene glycols, polyvinyl ethers, copolymers of poly(oxy)alkylene glycols or monoethers thereof and polyvinyl ethers, polyol esters, and polycarbonates. The lubricating oil composition for a refrigerator is used for a refrigerator that uses, as a refrigerant, a fluorine-containing organic compound, which is a refrigerant applicable to current car air conditioner systems or the like and has a specific polar structure, and has favorable sealing property, a low coefficient of friction factor in a sliding part, and excellent stability as well as excellent compatibility with the refrigerant.

  本发明提供了一种用于冰箱的润滑油组合物，其使用的基础油包括至少一种作为主要成分的含氧化合物，这些含氧化合物选自聚氧烷基乙二醇、聚乙烯醚、聚（氧）烷基乙二醇的共聚物或其单醚以及聚乙烯醚、多元醇酯和聚碳酸酯。冰箱润滑油组合物用于使用含氟有机化合物作为制冷剂的冰箱，该制冷剂是一种适用于当前汽车空调系统或类似系统的制冷剂，具有特定的极性结构，并具有良好的密封性能、滑动部件摩擦系数低、稳定性极佳以及与制冷剂的兼容性极佳。
• Lubricant oil composition for compression refrigerator
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：US10774252B2

  公开（公告）日：2020-09-15

  It is to provide a lubricating oil composition for a compression refrigerator, which is excellent in the thermal/chemical stability even when used in a compression refrigerator that uses a saturated fluorinated hydrocarbon refrigerant having a lower global warming potential and a fewer carbon atoms, by including in a base oil an organic compound having a double bond in a molecule, which is at least one kind selected from an organic compound having at least two non-conjugated double bonds in the molecule, a terpene compound having a double bond in the molecule, and C12 to C30 aliphatic unsaturated hydrocarbon having one double bond in the molecule.

  本发明旨在提供一种用于压缩式制冷机的润滑油组合物，该组合物即使用于使用全球变暖潜能值较低且碳原子数较少的饱和含氟碳氢化合物制冷剂的压缩式制冷机中，也具有优异的热稳定性/化学稳定性、在基础油中加入分子中含有双键的有机化合物，该双键至少选自分子中含有至少两个非共轭双键的有机化合物、分子中含有一个双键的萜烯化合物和分子中含有一个双键的 C12 至 C30 脂肪族不饱和烃中的一种。