(1r,2s,3s,4r)-4-Hydroxy-2-Methoxy-4-Methyl-3-[(2r,3r)-2-Methyl-3-(3-Methylbut-2-En-1-Yl)oxiran-2-Yl]cyclohexyl (Chloroacetyl)carbamate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1r,2s,3s,4r)-4-Hydroxy-2-Methoxy-4-Methyl-3-[(2r,3r)-2-Methyl-3-(3-Methylbut-2-En-1-Yl)oxiran-2-Yl]cyclohexyl (Chloroacetyl)carbamate
• 英文别名: [(1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]cyclohexyl] N-(2-chloroacetyl)carbamate
• 化学式: C₁₉H₃₀ClNO₆
• 分子量: 403.9
• InChiKey: OUUSPVSSNHLIGE-AGYLCKTBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  97.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• LOCAL TREATMENT OF NEUROFIBROMAS
  申请人：Chen Ruihong

  公开号：US20090118240A1

  公开（公告）日：2009-05-07

  A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.