Ether, methyl 1-octadecenyl

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Ether, methyl 1-octadecenyl
• 英文别名: (E)-1-methoxyoctadec-1-ene
• 化学式: C₁₉H₃₈O
• 分子量: 282.5
• InChiKey: ZDGCADFLCWUNMW-VHEBQXMUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  20
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same
  申请人：KAO CORPORATION

  公开号：EP0416564A2

  公开（公告）日：1991-03-13

  A novel aroyl ketone derivative represented by formula (I) is disclosed. Ar(COCH₂COR¹)n      (I) wherein R¹ represents a saturated or unsaturated hydrocarbon group having 1-24 carbon atoms, or a linear or branched alkoxyalkyl or alkenyloxyalkyl group having 1-24 carbon atoms, dialkylamino group having 1-24 carbon atoms, Ar represents a benzene or naphthalene ring which may be substituted with one or more hydroxyl groups, alkoxy groups having 1-24 carbon atoms, alkenyloxy groups having 1-24 carbon atoms, polyoxyleneoxy groups, or α-­methylenedioxy groups, and n denotes an integer of 1-4. An UV-ray absorber and cosmetic composition comprising the aroyl ketone derivative of formula (I) are also disclosed. Aroyl ketone derivative (I) of the present invention can provide an excellent UV-ray absorbing effect and has outstanding stability against light, and the UV-ray absorber or cosmetic composition containing the aroyl ketone derivative (I) can exhibit an excellent sunscreening effect.

  本发明公开了一种由式(I)代表的新型芳基酮衍生物。 Ar(COCH₂COR¹)n (I) 其中 R¹ 代表具有 1-24 个碳原子的饱和或不饱和烃基，或具有 1-24 个碳原子的直链或支链烷氧基或烯氧基烷基，具有 1-24 个碳原子的二烷基氨基，Ar 代表可被一个或多个羟基、具有 1-24 个碳原子的烷氧基、具有 1-24 个碳原子的烯氧基、聚氧乙烯氧基或 α-亚甲二氧基取代的苯环或萘环，n 表示 1-4 的整数。此外，还公开了一种紫外线吸收剂和包含式（I）丙酮衍生物的化妆品组合物。本发明的芳基酮衍生物（I）可提供优异的紫外线吸收效果，并具有出色的耐光稳定性，含有该芳基酮衍生物（I）的紫外线吸收剂或化妆品组合物可表现出优异的防晒效果。
• Cationic lipid
  申请人：DAIICHI SANKYO COMPANY, LIMITED

  公开号：US10731159B2

  公开（公告）日：2020-08-04

  The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic acid lipid particle containing the lipid particle, and a pharmaceutical composition containing the nucleic acid lipid particle as an active ingredient.

  本发明提供了一种由式（Ia）表示的化合物，作为一种新型阳离子脂质，可形成脂质颗粒，还提供了一种包含该化合物的脂质颗粒。本发明进一步提供了一种含有该脂质颗粒的核酸脂质颗粒，以及一种含有该核酸脂质颗粒作为活性成分的药物组合物。
• Methods related to volatile compounds in genitourinary cancers
  申请人：Lee Wen-Yee

  公开号：US10908162B2

  公开（公告）日：2021-02-02

  Embodiments are directed to methods of identifying a subject having prostate cancer or renal cell carcinoma; or prostate cancer risk assessment of a subject by determining level of at least one volatile organic compound from a sample from the subject where a significantly different level of the at least one volatile organic compound in the sample as compared to the level of the compound in a control sample is indicative of the presence of prostate cancer or renal cell carcinoma or low-risk prostate cancer or high-low prostate cancer in the subject.

  本发明的实施方案涉及识别患有前列腺癌或肾细胞癌的受试者的方法；或通过确定受试者样本中至少一种挥发性有机化合物的水平来评估受试者的前列腺癌风险的方法，其中样本中至少一种挥发性有机化合物的水平与对照样本中该化合物的水平相比存在显著差异，则表明受试者存在前列腺癌或肾细胞癌或低风险前列腺癌或高风险前列腺癌。
• NOVEL LIPID
  申请人：Daiichi Sankyo Company, Limited

  公开号：EP3020701B1

  公开（公告）日：2018-09-26
• EP2851369A2
  申请人：——

  公开号：EP2851369A2

  公开（公告）日：2015-03-25