(6Z)-6-[[3-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]propylamino]methylidene]cyclohexa-2,4-dien-1-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (6Z)-6-[[3-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]propylamino]methylidene]cyclohexa-2,4-dien-1-one
• 化学式: C₁₇H₁₈N₂O₂
• 分子量: 282.34
• InChiKey: BHBZPGSHCVSMEB-PMJBJKLVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Method for stabilizing a condensed phase composition including a cyclic ester in a process of manufacturing a polyester or of lactide
  申请人：Sulzer Chemtech AG

  公开号：US10059799B2

  公开（公告）日：2018-08-28

  A method for stabilizing a condensed phase composition in a process of manufacturing a polyester from cyclic ester monomer comprising the steps of devolatilizing a reaction mixture, which contains i) at least one polymerizable cyclic ester, ii) at least one catalyst and optionally at least one initiator, to produce a vapor stream and a molten residue, wherein the vapor stream includes mainly i) the at least one polymerizable cyclic ester and ii) the at least one catalyst and/or the at least one initiator and/or a reaction product or a residue of the at least one catalyst and/or the at least one initiator and condensing the vapor stream to form the condensed phase composition, wherein at least one polymerization inhibitor is added as stabilizer to the reaction mixture and/or to the condensed phase composition in an amount so that the degree of conversion of the polymerizable cyclic ester in the condensed phase composition is not more than 15%, wherein the degree of conversion is 100▪(c0−CF)/c0, wherein c0 is the initial concentration of the cyclic ester in the condensed phase composition obtained by the condensation of the vapor stream and CF is the concentration of the cyclic ester in the condensed phase composition after addition of 150 ppm of tin octoate as catalyst and of 100 mmol/kg of ethyl-hexanol as initiator to the condensed phase composition and a subsequent heat treatment of condensed phase composition under inert atmosphere conditions for 12 hours at 160° C.

  一种在利用环酯单体制造聚酯的工艺中稳定凝聚相组合物的方法，包括以下步骤：使反应混合物脱溶，该混合物含有 i) 至少一种可聚合环酯，ii) 至少一种催化剂和可选的至少一种引发剂，以产生蒸汽流和熔融残留物、其中蒸汽流主要包括 i) 至少一种可聚合环酯和 ii) 至少一种催化剂和/或至少一种引发剂和/或至少一种催化剂和/或至少一种引发剂的反应产物或残留物，冷凝蒸汽流形成冷凝相组合物、其中至少一种聚合抑制剂作为稳定剂加入反应混合物和/或缩合相组合物中，加入量使缩合相组合物中可聚合环酯的转化率不超过 15%，其中转化率为 100▪(c0-CF)/c0、其中，c0 是通过冷凝蒸汽流得到的冷凝相组合物中环酯的初始浓度，CF 是在冷凝相组合物中加入 150 ppm 的辛酸锡作为催化剂和 100 mmol/kg 的乙基己醇作为引发剂，并随后在惰性气氛条件下在 160 摄氏度下对冷凝相组合物进行 12 小时热处理后，冷凝相组合物中环酯的浓度。
• Continuous method for manufacturing a polyester from cyclic ester monomer
  申请人：Sulzer Chemtech AG

  公开号：US10066054B2

  公开（公告）日：2018-09-04

  A process of manufacturing a polyester from cyclic ester monomer comprises the steps of: a) providing a cyclic ester, b) polymerizing the cyclic ester in the presence of a catalyst and optionally an initiator in a reactor to form a reaction mixture comprising polyester and unreacted cyclic ester, wherein after the polymerization at least one polymerization inhibitor is added to the reaction mixture, wherein the polymerization inhibitor is selected from the group consisting of monoimines, diimines, mono alkyl phosphates according to the formula RPO4H2, wherein R is a C6-16 linear, branched or cyclic alkyl group, di alkyl phosphates according to the formula R2PO4H, wherein each R is independently a C6-16 linear, branched or cyclic alkyl group or a combination thereof, and phosphate esters according to the general formula (I) wherein at least one of R′, R″ and R″′ has the general structure as in general formula (II) wherein n>0 and Q is independently a C1-16 linear, branched or substituted alkyl group, and R is independently an H or linear, branched, cyclic or substituted alkyl group or a phenyl group derivative, and wherein any of R′, R″ and R″′ not having the general structure as in general formula (II) is independently an H or a linear, branched, cyclic or substituted alkyl group or a phenyl group derivative.

  利用环酯单体制造聚酯的工艺包括以下步骤a)提供环酯，b)在催化剂和可选引发剂存在下，在反应器中聚合环酯，形成包含聚酯和未反应环酯的反应混合物，其中聚合后向反应混合物中添加至少一种聚合抑制剂、其中聚合抑制剂选自由下列物质组成的组：单亚胺、二亚胺、式 RPO4H2 的单烷基磷酸酯（其中 R 是 C6-16 直链、支链或环状烷基）、式 R2PO4H 的二烷基磷酸酯（其中每个 R 独立地是 C6-16 直链、支链或环状烷基）、式 R2PO4H 的二烷基磷酸酯（其中每个 R 独立地是 C6-16 直链、支链或环状烷基）、式 R2PO4H 的二烷基磷酸酯（其中每个 R 独立地是 C6-16 直链、支链或环状烷基R′、R″和 R″′ 中至少有一个具有通式 (II) 中的一般结构，其中 n>0 和 Q 独立地为 C1-16 直链、支链或取代的烷基、R独立地为H或直链、支链、环状或取代的烷基或苯基衍生物，其中R′、R″和R″′中不具有通式（II）中结构的任何一个独立地为H或直链、支链、环状或取代的烷基或苯基衍生物。
• A CONTINUOUS METHOD FOR MANUFACTURING A POLYESTER FROM CYCLIC ESTER MONOMER
  申请人：Sulzer Chemtech AG

  公开号：EP3180385A1

  公开（公告）日：2017-06-21
• A METHOD FOR STABILIZING A CONDENSED PHASE COMPOSITION INCLUDING A CYCLIC ESTER IN A PROCESS OF MANUFACTURING A POLYESTER OR OF LACTIDE
  申请人：Sulzer Chemtech AG

  公开号：EP3194468A1

  公开（公告）日：2017-07-26
• A Continuous Method for Manufacturing a Polyester from Cyclic Ester Monomer
  申请人：Sulzer Chemtech AG

  公开号：US20170240697A1

  公开（公告）日：2017-08-24

  A process of manufacturing a polyester from cyclic ester monomer comprises the steps of: a) providing a cyclic ester, b) polymerizing the cyclic ester in the presence of a catalyst and optionally an initiator in a reactor to form a reaction mixture comprising polyester and unreacted cyclic ester, wherein after the polymerization at least one polymerization inhibitor is added to the reaction mixture, wherein the polymerization inhibitor is selected from the group consisting of monoimines, diimines, mono alkyl phosphates according to the formula RPO 4 H 2 , wherein R is a C 6-16 linear, branched or cyclic alkyl group, di alkyl phosphates according to the formula R 2 PO 4 H, wherein each R is independently a C 6-16 linear, branched or cyclic alkyl group or a combination thereof, and phosphate esters according to the general formula (I) wherein at least one of R′, R″ and R″′ has the general structure as in general formula (II) wherein n>0 and Q is independently a C 1-16 linear, branched or substituted alkyl group, and R is independently an H or linear, branched, cyclic or substituted alkyl group or a phenyl group derivative, and wherein any of R′, R″ and R″′ not having the general structure as in general formula (II) is independently an H or a linear, branched, cyclic or substituted alkyl group or a phenyl group derivative.