(S)-2-[(S)-1-({[(S)-1-(Hydrazinocarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester | 82265-54-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-[(S)-1-({[(S)-1-(Hydrazinocarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS: 82265-54-1
• 化学式: C₃₂H₄₃N₇O₇
• 分子量: 637.736
• InChiKey: FQFRGXAOUGPYBE-SDHOMARFSA-N

反应信息

• 作为反应物：
  描述：

  (S)-2-[(S)-1-({[(S)-1-(Hydrazinocarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 在 盐酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 2.0h， 以80%的产率得到(S)-Pyrrolidine-2-carboxylic acid [(S)-1-({[(S)-1-(hydrazinocarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-amide; hydrochloride
  参考文献：
  名称：

  Peptide conformations. 15. One- and two-dimensional proton, carbon-13 and nitrogen-15 NMR studies of cyclo(Pro-Phe-Gly-Phe-Gly)n (n = 1, 2): selective complexation of lithium ions (n = 1) and potassium ions (n = 2)

  摘要：

  DOI：

  10.1021/ja00381a006
• 作为产物：
  描述：

  (S)-2-[(S)-1-({[(S)-1-(Methoxycarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以81%的产率得到(S)-2-[(S)-1-({[(S)-1-(Hydrazinocarbonylmethyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
  参考文献：
  名称：

  Peptide conformations. 15. One- and two-dimensional proton, carbon-13 and nitrogen-15 NMR studies of cyclo(Pro-Phe-Gly-Phe-Gly)n (n = 1, 2): selective complexation of lithium ions (n = 1) and potassium ions (n = 2)

  摘要：

  DOI：

  10.1021/ja00381a006