| 97347-08-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 97347-08-5
• 化学式: C₂₃H₄₂N₄O₁₇
• 分子量: 646.603
• InChiKey: KGGYAIMVUGZJAG-WAXDUETMSA-N

反应信息

• 作为产物：
  描述：

  O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-(1-6)-O-(2,3,4-tri-O-acetyl-β-D-glucopyranosyl)-(1-6)-2,3,4-tri-O-acetyl-1-N-(1-ethyl-N-(benzyloxycarbonyl)-L-glutam-5-oyl)-α-D-glucopyranosylamine 在 一水合肼 作用下， 反应 24.0h， 生成
  参考文献：
  名称：

  Synthesis of N-glycopeptides and a neoglycoprotein

  摘要：

  O-(alpha-D-Glucopyranosyl)-(1----6)-O-beta-D-glucopyranosyl-(1----6)-1-N -(glycylglycylglycyl-L-seryl-L-leucyl-L-glutam-5-oyl)-alpha- D -glucopyranosylamine has been prepared, as a model of a derivative possibly present in the glomerular basement membrane of rats, by condensation of the corresponding L-glutamyl derivative of the trisaccharide with the pentapeptide in the presence of O,O-diethyl cyanophosphonate. Protective groups were removed by O-deacetylation, deethoxylation, and hydrogenolysis. The glutamyl derivative of the trisaccharide was also converted into the acyl azide which was condensed with bovine serum albumin to form a neoglycoprotein.

  DOI：

  10.1016/0008-6215(85)90014-x