(E)-(S)-4-(tert-Butyl-dimethyl-silanyloxy)-hex-2-enoic acid ethyl ester | 130145-84-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-(S)-4-(tert-Butyl-dimethyl-silanyloxy)-hex-2-enoic acid ethyl ester
• CAS: 130145-84-5
• 化学式: C₁₄H₂₈O₃Si
• 分子量: 272.46
• InChiKey: GREXHJYMVQOYDH-IIANPFDCSA-N

反应信息

• 作为反应物：
  描述：

  (E)-(S)-4-(tert-Butyl-dimethyl-silanyloxy)-hex-2-enoic acid ethyl ester 在 草酰氯 、 二异丁基氢化铝 、 二甲基亚砜 、 三乙胺 作用下， 生成 (S)-4-(TBDMSO)-2-hexenal
  参考文献：
  名称：

  Conformational Studies of Chiral .alpha.,.beta.-Unsaturated Aldehydes

  摘要：

  The conformational profiles for chiral alpha,beta-unsaturated aldehydes have been studied by a combination of ab initio MO methods and the variable-temperature MMR technique. The s-trans rotational isomer around the C-sp2-C-sp2 single bond is more stable than the s-cis conformer by similar to 500 cal/mol in chloroform. This difference is 950 cal/mol according to ab initio calculations at the MP2/6-31G* level of theory. The silyl ethers, 3a-d, prefer the C-O eclipsed form while the methyl ethers, 6a-d, favor the C-H eclipsed conformation for rotations around the C-sp3-C-sp2 bond.

  DOI：

  10.1021/jo00094a043

文献信息

• High differentiation of the diastereo .pi.(C:C)-faces of acyclic bis-allylic systems in osmium tetroxide-catalyzed dihydroxylation
  作者：Seiki Saito、Yasuhisa Morikawa、Toshio Moriwake

  DOI：10.1021/jo00307a002

  日期：1990.9