(Z)-3-[(4R,5R,4'S,5'R)-5'-(Bis-ethylsulfanyl-methyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl]-acrylic acid methyl ester | 143833-60-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-3-[(4R,5R,4'S,5'R)-5'-(Bis-ethylsulfanyl-methyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl]-acrylic acid methyl ester
• CAS: 143833-60-7
• 化学式: C₁₉H₃₂O₆S₂
• 分子量: 420.591
• InChiKey: WPOCUQOZEVQHCN-DMRZNYOFSA-N

反应信息

• 作为反应物：
  描述：

  (Z)-3-[(4R,5R,4'S,5'R)-5'-(Bis-ethylsulfanyl-methyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl]-acrylic acid methyl ester 在 偶氮二异丁腈 、 三正丁基氢锡 作用下， 以 甲苯 为溶剂， 以77%的产率得到((3aR,5aR,8aS,8bR)-5-Ethylsulfanyl-2,2,7,7-tetramethyl-hexahydro-benzo[1,2-d;3,4-d']bis[1,3]dioxol-4-yl)-acetic acid methyl ester
  参考文献：
  名称：

  Synthesis of branched chain cyclitols: preparation of some useful chiral building blocks

  摘要：

  The conveniently functionalized carbohydrate intermediates 1-4 and 9 undergo 6-exo free radical intramolecular cyclization giving branched chain cyclitols in good yield and low to good diastereoselectivity. These compounds are useful chiral building blocks for further manipulation.

  DOI：

  10.1016/s0957-4166(00)80501-7