2-[2-Chloro-3-methyl-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-4,4-dimethyl-3-oxo-pentanoic acid 4-nitro-benzyl ester | 146937-50-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: 2-[2-Chloro-3-methyl-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-4,4-dimethyl-3-oxo-pentanoic acid 4-nitro-benzyl ester
• CAS: 146937-50-0
• 化学式: C₂₆H₂₈ClN₃O₈
• 分子量: 545.977
• InChiKey: OYXWJVPHUMELMC-UHFFFAOYSA-N

物化性质

• 沸点：
  774.8±60.0 °C(predicted)
• 密度：
  1.37±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  2-[2-Chloro-3-methyl-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-4,4-dimethyl-3-oxo-pentanoic acid 4-nitro-benzyl ester 在 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 以22.5%的产率得到
  参考文献：
  名称：

  Are 6-acylamino oxazoline stable compounds?

  摘要：

  The 6-acylamino oxapenem 10 is no isolable compound, but rearranges to the isomeric oxazoline 9 under the conditions of its formation. However, 6-azido (5), 6-imino (12) as well as 6-carbamoyl oxapenems (14) were prepared for the first time.

  DOI：

  10.1016/s0040-4039(00)60568-3
• 作为产物：
  描述：

  4,4-Dimethyl-2-[(2S,3R)-3-methyl-2-methylsulfanyl-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-oxo-pentanoic acid 4-nitro-benzyl ester 在 氯 作用下， 以 二氯甲烷 为溶剂， 生成 2-[2-Chloro-3-methyl-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-4,4-dimethyl-3-oxo-pentanoic acid 4-nitro-benzyl ester
  参考文献：
  名称：

  Are 6-acylamino oxazoline stable compounds?

  摘要：

  The 6-acylamino oxapenem 10 is no isolable compound, but rearranges to the isomeric oxazoline 9 under the conditions of its formation. However, 6-azido (5), 6-imino (12) as well as 6-carbamoyl oxapenems (14) were prepared for the first time.

  DOI：

  10.1016/s0040-4039(00)60568-3