(R)-5-((S)-Benzylamino-phenyl-methyl)-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one | 291522-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R)-5-((S)-Benzylamino-phenyl-methyl)-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one
• CAS: 291522-94-6
• 化学式: C₂₆H₂₈N₂O₂
• 分子量: 400.521
• InChiKey: CFKCWTJUSGBVPC-USZFVNFHSA-N

反应信息

• 作为反应物：
  描述：

  (R)-5-((S)-Benzylamino-phenyl-methyl)-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one 在 四溴化碳 、 三乙胺 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 以52%的产率得到(1S,4R,8aR)-2-Benzyl-1,4-diphenyl-hexahydro-pyrrolo[1,2-a]pyrazin-6-one
  参考文献：
  名称：

  Ytterbium triflate-catalyzed reactions of imines with a chiral non-racemic silyloxypyrrole

  摘要：

  In the presence of a catalytic amount of ytterbium triflate the reactions of various aromatic imines with a chiral non-racemic silyloxypyrrole proceeded smoothly to afford the corresponding aldol-type adducts in go od yields and diastereoselectivities. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00625-0
• 作为产物：
  描述：

  [(2R)-2-[2-[(benzylamino)-phenylmethyl]-5-oxo-2H-pyrrol-1-yl]-2-phenylethyl] benzoate 在 palladium on activated charcoal sodium hydroxide 、 氢气 作用下， 以 甲醇 为溶剂， 生成 (R)-5-((S)-Benzylamino-phenyl-methyl)-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one
  参考文献：
  名称：

  Ytterbium triflate-catalyzed reactions of imines with a chiral non-racemic silyloxypyrrole

  摘要：

  In the presence of a catalytic amount of ytterbium triflate the reactions of various aromatic imines with a chiral non-racemic silyloxypyrrole proceeded smoothly to afford the corresponding aldol-type adducts in go od yields and diastereoselectivities. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00625-0