| 1094731-33-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1094731-33-5
• 化学式: C₂₇H₅₂O₆Si₂
• 分子量: 528.877
• InChiKey: YAWRHRJNTXWFBI-IQZTVSQCSA-N

反应信息

• 作为反应物：
  描述：

  在 4-二甲氨基吡啶 、 2-甲基-6-硝基苯甲酸酐 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以80%的产率得到
  参考文献：
  名称：

  Enantioselective total synthesis of 13-O-brefeldin A

  摘要：

  An enantioselective route to the title compound, a heteroatom Substituted close analogue of natural brefeldin A, is described. As a key step in the whole synthesis, concatenation of the lower chain and the cyclopentanone-Upper chain moiety was achieved using a Rh-catalyzed Michael addition of a vinyl boronic acid to an enone, which effectively eliminated the problems encountered with the corresponding cuprate protocol and exemplified the potential of the strategy in synthesizing similar analogues. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.09.065
• 作为产物：
  描述：

  在 2-甲基-2-丁烯 、 sodium chlorite 、 H₄NaO₅P 作用下， 以 水 、 叔丁醇 为溶剂， 反应 24.0h， 以43 mg的产率得到
  参考文献：
  名称：

  Enantioselective total synthesis of 13-O-brefeldin A

  摘要：

  An enantioselective route to the title compound, a heteroatom Substituted close analogue of natural brefeldin A, is described. As a key step in the whole synthesis, concatenation of the lower chain and the cyclopentanone-Upper chain moiety was achieved using a Rh-catalyzed Michael addition of a vinyl boronic acid to an enone, which effectively eliminated the problems encountered with the corresponding cuprate protocol and exemplified the potential of the strategy in synthesizing similar analogues. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.09.065