9-decenyl 3-O-(β-d-galactofuranosyl)-α-D-mannopyranoside | 1438222-11-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-decenyl 3-O-(β-d-galactofuranosyl)-α-D-mannopyranoside
• CAS: 1438222-11-7
• 化学式: C₂₂H₄₀O₁₁
• 分子量: 480.553
• InChiKey: XLWQMYJXERHSTJ-NZDOGBCLSA-N

反应信息

• 作为产物：
  描述：

  在 甲醇 、 sodium methylate 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 9-decenyl 3-O-(β-d-galactofuranosyl)-α-D-mannopyranoside 、 9-decenyl 3-O-(β-d-galactofuranosyl)-β-D-mannopyranoside
  参考文献：
  名称：

  Synthetic tools for the characterization of galactofuranosyl transferases: glycosylations via acylated glycosyl iodides

  摘要：

  With the aim of developing synthetic tools for the characterization of galactofuranosyltransferases, the synthesis of 9-decenyl glycosides of D-Manp, D-Galf, and beta-D-Galf-(1 -> 3)-D-Manp was targeted. The interest in the alkenyl aglycone arises via potential conjugation reactions, once the terminal double bond has been conveniently functionalized. The glycosylation of beta-D-Galf-(1 -> 3)-D-Manp was attempted by two different approaches: the trichloroacetimidate method and the glycosylation via the glycosyl iodide. The conditions for the latter were established on the basis of glycosylation assays of per-O-acetylmannose. On the other hand, the study of glycosylation reactions via per-O-benzoylated galactofuranosyl iodide confirms the versatility of glycosyl iodides as donors. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2013.03.032