| 1040750-60-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• CAS: 1040750-60-4
• 化学式: C₇₃H₁₄O₄
• 分子量: 954.912
• InChiKey: PTPXZMXJJHJWKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17.21
• 重原子数：
  77.0
• 可旋转键数：
  8.0
• 环数：
  33.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  、 O,O'-(2-((2-azidoethoxy)carbonyl)-2-methylpropane-1,3-diyl) bis(2-(trimethylsilyl)ethyl) disuccinate 在 copper(II) sulfate 、 sodium ascorbate 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 24.0h， 以84%的产率得到
  参考文献：
  名称：

  Nanorods versus Nanovesicles from Amphiphilic Dendrofullerenes

  摘要：

  Three new amphiphilic dendrofullerenes endowed with 4, 8, and 16 carboxylic groups have been efficiently prepared by using a click chemistry methodology. These amphiphilic fullerene derivatives aggregate forming micelles, nanorods, or hollow vesicles depending on the concentration and on the solid substrate.

  DOI：

  10.1021/ja206769a
• 作为产物：
  描述：

  di(pent-4-yn-1-yl) malonate 、 足球烯 在 碘 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 甲苯 为溶剂， 以44%的产率得到
  参考文献：
  名称：

  Click chemistry with fullerene derivatives

  摘要：

  C(60) derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper-mediated Huisgen 1,3-dipolar cycloaddition conditions leading to 1,2,3-triazole derivatives. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.064

文献信息

• Antiviral activity of self-assembled glycodendro[60]fullerene monoadducts
  作者：Antonio Muñoz、Beatriz M. Illescas、Joanna Luczkowiak、Fátima Lasala、Renato Ribeiro-Viana、Javier Rojo、Rafael Delgado、Nazario Martín

  DOI：10.1039/c7tb01379e

  日期：——

  A series of amphiphilic glycodendro[60]fullerene monoadducts were efficiently synthesized using the CuAAC "click chemistry" approach. These glycodendrofullerenes can self-assemble in aqueous media, in a process favoured through π-π interactions between the [60]fullerene moieties. This aggregation process leads to big and well-defined compact micelles with a uniform size and spherical-shape. The supramolecular

  使用CuAAC“点击化学”方法可以有效地合成一系列两亲性糖基[60]富勒烯单加合物。这些糖烯富勒烯可以在水性介质中自组装，这是通过[60]富勒烯部分之间的π-π相互作用促进的过程。该聚集过程导致具有均匀尺寸和球形的大且定义明确的紧密胶束。使用电子显微镜（SEM和TEM），光散射方法（DLS）和X射线方法（SAXS和XRD）对超分子聚集体进行表征。
• Synthesis of fullerene building blocks bearing alkyne or azide groups and their subsequent functionalization by the copper mediated Huisgen 1,3-dipolar cycloaddition
  作者：Rossimiriam Pereira de Freitas、Julien Iehl、Béatrice Delavaux-Nicot、Jean-François Nierengarten

  DOI：10.1016/j.tet.2008.09.047

  日期：2008.12

  C-60 derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper mediated Huisgen 1,3-dipolar cycloaddition conditions. In general, the reactivity of C60 toward azides does not significantly compete with the cycloaddition leading to the desired 1,2,3-triazole derivatives and good yields can be obtained when fullerene derivatives with reasonable Solubility are used as starting materials. The electrochemical properties of the new fullerene derivatives have also been investigated by cyclic voltammetry (CV) and Osteryoung Square Wave Voltammetry (OSWV). (C) 2008 Elsevier Ltd. All rights reserved.