6-hydroxy-3-methyl-hexanoic acid ethyl ester | 135011-13-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-hydroxy-3-methyl-hexanoic acid ethyl ester
• 英文别名: ε-Oxy-δ-methyl-n-capronsaeure-aethylester；6-Hydroxy-3-methyl-hexansaeure-aethylester；2-Methyl-hexanol-(1)-saeure-(6)-aethylester；Ethyl(R)-6-Hydroxy-3-methylhexanoate；ethyl 6-hydroxy-3-methylhexanoate
• CAS: 135011-13-1
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: SSJQOTXWMLWHOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-甲基环己酮 在 Oxone 、 乙醇 作用下， 生成 6-hydroxy-3-methyl-hexanoic acid ethyl ester
  参考文献：
  名称：

  Baeyer; Villiger, Chemische Berichte, 1900, vol. 33, p. 860

  摘要：

  DOI：

文献信息

• PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
  申请人：Mitobridge, Inc.

  公开号：EP3359528B1

  公开（公告）日：2022-01-12
• [EN] UNSATURATED FATTY ACIDS AND THEIR USES IN THERAPY<br/>[FR] ACIDES GRAS INSATURES ET UTILISATIONS THERAPEUTIQUES
  申请人：COMMW SCIENT IND RES ORG

  公开号：WO2001046115A1

  公开（公告）日：2001-06-28

  This invention relates to a method for the treatment or prevention of coronary heart disease including the step of administering a polyunsaturated fatty acid or derivative thereof, said polyunsaturated fatty acid including: a linear chain of 18 carbon atoms, and two or more double bonds in the linear chain, wherein said polyunsaturated fatty acid is an n-1, n-2, n-3, n-4 or n-5 fatty acid, but excluding 183n-3 (Δ9,12,15) .
• [EN] PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF<br/>[FR] AGONISTES DE PPAR, COMPOSÉS, COMPOSITIONS PHARMACEUTIQUES ET MÉTHODES D'UTILISATION DE CEUX-CI
  申请人：MITOBRIDGE INC

  公开号：WO2017062468A1

  公开（公告）日：2017-04-13

  Provided herein are compounds and compositions useful in increasing PPAR8 activity. The compounds and compositions provided herein are useful for the treatment of PPAR8 related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).