α-elaeostearylalkohol | 61361-73-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: α-elaeostearylalkohol
• 英文别名: alpha-Eleostearyl alcohol；(9Z,11E,13E)-octadeca-9,11,13-trien-1-ol
• CAS: 61361-73-7
• 化学式: C₁₈H₃₂O
• 分子量: 264.451
• InChiKey: HOUDCAFABFEPLY-WPOADVJFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  α-elaeostearylalkohol 150.0 ℃ 、26.66 Pa 条件下， 生成 octadeca-9t,11t,13t-trien-1-ol
  参考文献：
  名称：

  Lighthelm et al., Journal of the Chemical Society, 1950, p. 3187,3190

  摘要：

  DOI：
• 作为产物：
  描述：

  alpha-桐酸 在 lithium aluminium tetrahydride 、 乙醚 作用下， 生成 α-elaeostearylalkohol
  参考文献：
  名称：

  Lighthelm et al., Journal of the Chemical Society, 1950, p. 3187,3190

  摘要：

  DOI：

文献信息

• Mixture of amides and cosmetic compositions comprising said mixture
  申请人：KAO CORPORATION, S.A.

  公开号：EP2202219A1

  公开（公告）日：2010-06-30

  A mixture of amides of the following formula (I) is disclosed wherein - R1 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms; - R2 and R3 represent independently, a hydrogen atom or a linear or branched alkyl group having 1 to 5 carbon atoms which is optionally hydroxylated, provided that R2 and R3 are not a hydrogen atom at the same time; - n has a value in the range of 0.2 to lower than 3; characterized in that said mixture comprises: - amides (a) of formula (I) wherein R represents a C6-C24 alkyl or alkenyl group having even number of carbon atoms and at least a 95 wt.% of linearity; and - amides (b) of formula (I) wherein R represents a C5-C23 alkyl or alkenyl group having odd or odd and even number of carbon atoms and a 35-85 wt.% of linearity; and cosmetic compositions comprising said mixture, particularly dying compositions.

  公开了下式（I）的酰胺混合物 其中 - R1 代表氢原子或具有 1 至 5 个碳原子的烷基； - R2 和 R3 分别代表氢原子或具有 1 至 5 个碳原子的直链或支链烷基，该烷基可选择羟化，但 R2 和 R3 不能同时代表氢原子； - n 的值在 0.2 至小于 3 的范围内； 其特征在于所述混合物包括 - 式 (I) 的酰胺 (a) 其中 R 代表具有偶数个碳原子的 C6-C24 烷基或烯基，其线性度至少为 95 wt.%；以及 - 式 (I) 的酰胺 (b)，其中 R 代表碳原子数为奇数或奇数和偶数的 C5-C23 烷基或烯基，线性度为 35-85%； 以及包含上述混合物的化妆品组合物，尤其是染色组合物。
• Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
  申请人：Metaproteomics, LLC

  公开号：EP2737897A2

  公开（公告）日：2014-06-04

  The present invention relates to compositions consisting essentially of a therapeutically effective amount of a compound selected from the group consisting of tetrahydro-isohumulone, tetrahydro-isocohumulone, and tetrahydro-isoadhumulone; and metformin, to be used in the treatment of an insulin related disorder, diabetes, obesity, or a cardiovascular disease.

  本发明涉及主要由治疗有效量的选自四氢-异胡麻酮、四氢-异胡麻酮和四氢-异胡麻酮组成的化合物和二甲双胍组成的组合物，用于治疗胰岛素相关疾病、糖尿病、肥胖症或心血管疾病。
• Methods and compositions for the treatment of diabetes, the reduction of body fat, improvement of insulin sensitivity, reduction of hyperglycemia, and reduction of hypercholesterolemia with chromium complexes, conjugated fatty acids, and/or conjugated fatty alcohols
  申请人：——

  公开号：US20020081315A1

  公开（公告）日：2002-06-27

  A composition for treating insulin-dependent diabetes, reducing body fat, improving insulin sensitivity, reducing hyperglycemia, and reducing hypercholesterolemia with at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is disclosed. A method of treating a subject suffering from insulin-dependent diabetes by administering a composition that includes at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is similarly provided. The administration of a composition containing an effective dose of at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol for the treatment of obesity is likewise provided. PATENT

  本发明公开了一种用于治疗胰岛素依赖型糖尿病、降低体脂、改善胰岛素敏感性、降低高血糖和降低高胆固醇血症的组合物，其中含有至少一种铬络合物和一种共轭脂肪酸或共轭脂肪醇。同样还提供了一种通过服用包含至少一种铬络合物和共轭脂肪酸或共轭脂肪醇的组合物来治疗胰岛素依赖型糖尿病患者的方法。同样还提供了施用含有有效剂量的至少一种铬络合物和共轭脂肪酸或共轭脂肪醇的组合物治疗肥胖症的方法。专利
• Methods for the treatment of diabetes, the reduction of body fat, improvement of insulin sensitivity, reduction of hyperglycemia, and reduction of hypercholesterolemia with chromium complexes, conjugated fatty acids, and/or conjugated fatty alcohols
  申请人：——

  公开号：US20030091654A1

  公开（公告）日：2003-05-15

  A composition for treating insulin-dependent diabetes, reducing body fat, improving insulin sensitivity, reducing hyperglycemia, and reducing hypercholesterolemia with at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is disclosed. A method of treating a subject suffering from insulin-dependent diabetes by administering a composition that includes at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is similarly provided. The administration of a composition containing an effective dose of at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol for the treatment of obesity is likewise provided.

  本发明公开了一种用于治疗胰岛素依赖型糖尿病、降低体脂、改善胰岛素敏感性、降低高血糖和降低高胆固醇血症的组合物，其中含有至少一种铬络合物和一种共轭脂肪酸或共轭脂肪醇。同样还提供了一种通过服用包含至少一种铬络合物和共轭脂肪酸或共轭脂肪醇的组合物来治疗胰岛素依赖型糖尿病患者的方法。同样还提供了施用含有有效剂量的至少一种铬络合物和共轭脂肪酸或共轭脂肪醇的组合物治疗肥胖症的方法。
• CHROMIUM CONTAINING COMPOSITIONS FOR THE TREATMENT OF DIABETES, THE REDUCTION OF BODY FAT, IMPROVEMENT OF INSULIN SENSITIVITY AND REDUCTION OF HYPERGLYCEMIA AND HYPERCHOLESTEREMIA
  申请人：Nutrition 21, Inc.

  公开号：EP1357977A2

  公开（公告）日：2003-11-05