N1-((1H-indol-2-yl)methylene)-N2,N2-dimethylethane-1,2-diamine | 1409949-76-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: N1-((1H-indol-2-yl)methylene)-N2,N2-dimethylethane-1,2-diamine
• 英文别名: 2-(1H-indol-2-ylmethylideneamino)-N,N-dimethylethanamine
• CAS: 1409949-76-3
• 化学式: C₁₃H₁₇N₃
• 分子量: 215.298
• InChiKey: DWDYONCWDUTYDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  31.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N1-((1H-indol-2-yl)methylene)-N2,N2-dimethylethane-1,2-diamine 以 甲苯 为溶剂， 反应 20.0h， 生成
  参考文献：
  名称：

  2-N,N-二甲氨基-乙烯-亚氨基官能化吲哚配体稀土金属配合物的合成与表征及其对亚胺氢化硅烷化的催化活性

  摘要：

  2 - N , N-二甲基氨基-亚乙基-亚氨基官能化吲哚前配体2-(Me 2 NCH 2 CH 2 N = CH)C 8 H 5 NH (H L ) 与[(Me 3 Si) 2 N]的反应3 RE(μ-Cl)Li(THF) 3在甲苯中得到一系列稀土金属氨基络合物 [κ 3 -( N , N , N )-2-(Me 2 NCH 2 CH 2 N = CH)C 8 H 5 N]RE[N(SiMe 3 )2 ] 2 (RE = Y ( 1a ), Nd ( 1b ), Sm ( 1c ), Gd ( 1d ), Dy ( 1e ), Er ( 1f ), 和 Yb ( 1g ))。H L与 [(Me 3 Si) 2 N] 3 Eu(μ-Cl)Li(THF) 3反应生成二聚体形式的铕(II)络合物[{(η 5 -μ-η 1 : η 1 :η 1 )-2-(Me 2 NCH 2 CH 2 N=CH )C

  DOI：

  10.1021/acs.organomet.2c00412
• 作为产物：
  描述：

  1H-吲哚-2-甲醛 、 N,N-二甲基乙二胺 在 magnesium sulfate 作用下， 以85 %的产率得到N1-((1H-indol-2-yl)methylene)-N2,N2-dimethylethane-1,2-diamine
  参考文献：
  名称：

  2-N,N-二甲氨基-乙烯-亚氨基官能化吲哚配体稀土金属配合物的合成与表征及其对亚胺氢化硅烷化的催化活性

  摘要：

  2 - N , N-二甲基氨基-亚乙基-亚氨基官能化吲哚前配体2-(Me 2 NCH 2 CH 2 N = CH)C 8 H 5 NH (H L ) 与[(Me 3 Si) 2 N]的反应3 RE(μ-Cl)Li(THF) 3在甲苯中得到一系列稀土金属氨基络合物 [κ 3 -( N , N , N )-2-(Me 2 NCH 2 CH 2 N = CH)C 8 H 5 N]RE[N(SiMe 3 )2 ] 2 (RE = Y ( 1a ), Nd ( 1b ), Sm ( 1c ), Gd ( 1d ), Dy ( 1e ), Er ( 1f ), 和 Yb ( 1g ))。H L与 [(Me 3 Si) 2 N] 3 Eu(μ-Cl)Li(THF) 3反应生成二聚体形式的铕(II)络合物[{(η 5 -μ-η 1 : η 1 :η 1 )-2-(Me 2 NCH 2 CH 2 N=CH )C

  DOI：

  10.1021/acs.organomet.2c00412

文献信息

• NON-CYCLOPENTADIENYL-BASED CHROMIUM CATALYSTS FOR OLEFIN POLYMERIZATION
  申请人：Christianson Matthew D.

  公开号：US20150148502A1

  公开（公告）日：2015-05-28

  Provided is a non-cyclopentadienyl-based chromium-ligand complex, preferably a chromium-ligand complex of formula (J): LCr(R A ) m (D) k (J), wherein L is a non-Cp monoanionic ligand; Cr (chromium) is in a formal oxidation state of +3 or +2; when Cr formally is Cr +3 , either m is 1 and R A is hydrocarbylene (a hydrocarbylene chromium-ligand complex of formula (J)) or m is 2 and each R A independently is hydrocarbyl (a dihydrocarbyl chromium-ligand complex of formula (J)), wherein each hydrocarbyl or hydrocarbylene of R A independently is unsubstituted or substituted by from 1 to 5 R AS ; each R AS independently is a neutral aprotic heteroalkyl, neutral aprotic heterocycloalkyl, neutral aprotic heteroaryl, or neutral aprotic aryl; when Cr formally is Cr +2 , m is 1 and R A is hydrocarbyl (a hydrocarbyl chromium-ligand complex of formula (J)); k is an integer of 0 or 1; D is absent when k is 0 or D is a neutral ligand when k is 1; wherein the chromium-ligand complex of formula (J) is overall neutral and lacks a cyclopentadienyl-based (Cp-based) moiety. Also provided is a chromium catalyst comprising or prepared from the complex. Also provided is a process of making the catalyst and a process employing the chromium catalyst for polymerizing the olefin monomer, especially a straight chain 1-alkene, to prepare the polyolefin, especially a partially chain-straightened poly(1-alkene) or olefin block copolymer. Further provided is the partially chain-straightened poly(1-alkene) or olefin block copolymer prepared thereby. Also provided is a high throughput workflow.

  提供的是一种非环戊二烯基铬配合物，优选为式（J）的铬配合物：LCr（RA）m（D）k（J），其中L是非Cp单阴离子配体；Cr（铬）处于+3或+2的形式氧化态；当Cr形式上为Cr+3时，m为1且RA为烃基亚烷基（式（J）的烃基亚烷基铬配合物）或m为2且每个RA独立为烃基（式（J）的二烃基铬配合物），其中每个RA的烃基或烃基亚烷基均为未取代或被1至5个RAS取代；每个RAS独立为中性无水脂肪族杂基、中性无水杂环脂肪族基、中性无水杂环芳基或中性无水芳基；当Cr形式上为Cr+2时，m为1且RA为烃基（式（J）的烃基铬配合物）；k为0或1的整数；当k为0时D不存在，当k为1时D为中性配体；其中式（J）的铬配合物总体上是中性的并且不含环戊二烯基（Cp基）结构。还提供了一种包含或由该配合物制备的铬催化剂。还提供了一种制备催化剂的方法以及使用铬催化剂聚合烯烃单体的方法，尤其是直链1-烯烃，以制备聚烯烃，特别是部分链条直化的聚（1-烯烃）或烯烃嵌段共聚物。还提供了由此制备的部分链条直化的聚（1-烯烃）或烯烃嵌段共聚物。还提供了一种高通量工作流程。
• Non-cyclopentadienyl-based chromium catalysts for olefin polymerization
  申请人：Christianson Matthew D.

  公开号：US09296836B2

  公开（公告）日：2016-03-29

  Provided is a non-cyclopentadienyl-based chromium-ligand complex, preferably a chromium-ligand complex of formula (J): LCr(RA)m(D)k (J), wherein L is a non-Cp monoanionic ligand; Cr (chromium) is in a formal oxidation state of +3 or +2; when Cr formally is Cr+3, either m is 1 and RA is hydrocarbylene (a hydrocarbylene chromium-ligand complex of formula (J)) or m is 2 and each RA independently is hydrocarbyl (a dihydrocarbyl chromium-ligand complex of formula (J)), wherein each hydrocarbyl or hydrocarbylene of RA independently is unsubstituted or substituted by from 1 to 5 RAS; each RAS independently is a neutral aprotic heteroalkyl, neutral aprotic heterocycloalkyl, neutral aprotic heteroaryl, or neutral aprotic aryl; when Cr formally is Cr+2, m is 1 and RA is hydrocarbyl (a hydrocarbyl chromium-ligand complex of formula (J)); k is an integer of 0 or 1; D is absent when k is 0 or D is a neutral ligand when k is 1; wherein the chromium-ligand complex of formula (J) is overall neutral and lacks a cyclopentadienyl-based (Cp-based) moiety. Also provided is a chromium catalyst comprising or prepared from the complex. Also provided is a process of making the catalyst and a process employing the chromium catalyst for polymerizing the olefin monomer, especially a straight chain 1-alkene, to prepare the polyolefin, especially a partially chain-straightened poly(1-alkene) or olefin block copolymer. Further provided is the partially chain-straightened poly(1-alkene) or olefin block copolymer prepared thereby. Also provided is a high throughput workflow.

  提供的是一种非环戊二烯基铬配体复合物，优选为公式（J）的铬配体复合物：LCr（RA）m（D）k（J），其中L是非Cp单负离子配体；Cr（铬）处于+3或+2的形式氧化态；当Cr形式上是Cr+3时，m为1且RA为烃基（公式（J）的烃基铬配体复合物）或m为2且每个RA独立地为烃基（公式（J）的二烃基铬配体复合物），其中每个RA的烃基或烃基亚烷基独立地未被取代或被1至5个RAS取代；每个RAS独立地为中性的无水脂肪族杂基、中性的无水杂环烷基、中性的无水杂芳基或中性的无水芳基；当Cr形式上是Cr+2时，m为1且RA为烃基（公式（J）的烃基铬配体复合物）；k为0或1的整数；当k为0时，D不存在，当k为1时，D为中性配体；其中公式（J）的铬配体复合物总体上是中性的，并且缺少环戊二烯基（Cp基）基团。还提供了由该复合物组成或制备的铬催化剂。还提供了制备该催化剂的方法以及使用铬催化剂聚合烯烃单体的方法，特别是直链1-烯烃，以制备聚烯烃，特别是部分链条直化的聚（1-烯烃）或烯烃嵌段共聚物。进一步提供了由此制备的部分链条直化的聚（1-烯烃）或烯烃嵌段共聚物。还提供了高通量工作流程。