10,10-Dimethyl-undecansaeure-amid | 5556-37-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10,10-Dimethyl-undecansaeure-amid
• 英文别名: neotridecanamide；10,10-Dimethylundecanamide
• CAS: 5556-37-6
• 化学式: C₁₃H₂₇NO
• 分子量: 213.363
• InChiKey: MIQFARBBFFESLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  Neotridecanoylchlorid 在 ammonium hydroxide 作用下， 生成 10,10-Dimethyl-undecansaeure-amid
  参考文献：
  名称：

  Buu-Hoi,N.P. et al., Bulletin de la Societe Chimique de France, 1965, p. 3640 - 3643

  摘要：

  DOI：

文献信息

• PROCESS FOR ALKENYLATING CARBOXAMIDES
  申请人：Staffel Wolfgang

  公开号：US20090131657A1

  公开（公告）日：2009-05-21

  The present invention relates to a process for preparing N-(1-alkenyl)carboxamides of the formula I, which comprises reacting a carboxamide of the formula II with an alkyne of the formula III in the presence of a catalyst selected from among carbonyl complexes, halides and oxides of rhenium, manganese, tungsten, molybdenum, chromium and iron.

  本发明涉及一种制备式I的N-(1-烯基)羧酰胺的方法，包括在选择自铼、锰、钨、钼、铬和铁的羰基配合物、卤化物和氧化物之一作为催化剂的情况下，将式II的羧酰胺与式III的炔烃反应。
• N-alkyl neoalkanamide insect repellents
  申请人：Colgate-Palmolive Company

  公开号：EP0367257A1

  公开（公告）日：1990-05-09

  N-lower alkyl neoalkanamides (N-lower alkyl trialkyl­acetamides of certain types) of 1 to 4 carbon atoms in the lower alkyl thereof and of 5 to 14 carbon atoms in the neoalkanoyl (or trialkylacetyl) group, e.g., N-methyl- and N-ethyl neodecan­amides and N-methyl and N-ethyl neotridecanamides, are new compounds, secondary amides which have insect repellent properties, being especially effective against cockroaches, e.g., the German cockroach. However, they are also useful as repellents for other insects, including American cockroaches, mosquitoes, flies, fleas, ants, and lice. Additionally, they may repel arachnids, such as spiders, ticks and mites. The new neoalkanamides may be synthesized easily, as by reacting a primary lower alkyl amine with a neoalkanoyl halide, e.g. by reacting methyl amine or ethyl amine with neodecanoyl chloride. The most effective of the described amides for insect repellency are normally liquid and are sufficiently volatile to be detectable in air by insects. They may be applied directly to surfaces to be treated or they may be incorporated in detergent compositions, such as build laundry deter­gents, floor and wall cleaners, rug cleaners and shampoos, hair shampoos, and liquid and bar soaps, and have been found to be sufficiently substantive to the substrate being washed so as to impart insect repelling properties to it. They may be dissolved, dispersed or emulsified (emulsions are considered to be special cases of dispersions) in appropriate liquid media and may be applied to surfaces to be made insect repellent, as by spraying, brushing, wiping or other suitable processes, includ­ing "aerosol" spraying from pressurized containers. They have been found to be of long lasting effectiveness, with significant and measurable insect repellency being obtainable for as long as two weeks after application. The described N-lower alkyl neoalkanamides are stable during normal uses, relatively low in manufacturing cost, of high substantivities to substrates, economical to use, unobjectionable in odor to humans, and harmless to humans and animals, and to the environment.

  N-低烷基新烷基酰胺（某些类型的 N-低烷基三烷基乙酰胺），其低烷基中含有 1 至 4 个碳原子，新烷酰基（或三烷基乙酰基）中含有 5 至 14 个碳原子，例如 N-甲基和 N-乙基新癸酰胺以及 N-甲基和 N-乙基新十三烷酰胺，是具有驱虫特性的仲酰胺类新化合物，对蟑螂（如德国蟑螂）特别有效。不过，它们也可用作其他昆虫的驱虫剂，包括美洲蟑螂、蚊子、苍蝇、跳蚤、蚂蚁和虱子。此外，它们还可以驱除蜘蛛、扁虱和螨虫等蛛形纲动物。新的新烷酰胺可以很容易地合成，例如通过伯低级烷基胺与新烷酰卤的反应，如通过甲基胺或乙基胺与新癸酰氯的反应。 所述酰胺中最有效的驱虫剂通常是液态的，具有足够的挥发性，昆虫可以在空气中检测到。它们可以直接涂抹在要处理的表面上，也可以加入洗涤剂组合物中，如制造洗衣粉、地板和墙壁清洁剂、地毯清洁剂和洗发水、洗发水、液体和条状肥皂。它们可以在适当的液体介质中溶解、分散或乳化（乳液被认为是分散体的特殊情况），并可以通过喷洒、刷洗、擦拭或其他适当的工艺，包括从加压容器中进行 "气溶胶 "喷洒，涂抹到需要驱虫的表面上。研究发现，这些产品具有持久的驱虫效果，在施用后的两周内都有明显的、可测量的驱虫效果。所述 N-低级烷基新烷酰胺在正常使用过程中性能稳定，制造成本相对较低，对基质的吸附性高，使用经济，对人体无异味，对人类、动物和环境无害。
• N-Aryl and N-cycloalkyl neoalkanamide insect repellents
  申请人：Colgate-Palmolive Company

  公开号：EP0499992A1

  公开（公告）日：1992-08-26

  N-monosubstituted neoalkanamides of 11 to 14 carbon atoms wherein the substituent on the amide nitrogen is cyclic (aromatic or cycloaliphatic, such as aryl or cycloalkyl) and of at least five carbon atoms, have been discovered to be insect repellent, providing that any aromatic substituent is unsubstituted at the ortho position and that when the neoalkanoyl moiety is pivaloyl the total number of carbon atoms in the N-cyclic neoalkanamide is at least 12. Such neoalkanamides are useful as repellents against cockroaches, including American, German and Oriental cockroaches, and are also effective against mosquitoes (both Anopheles and Aedes), black flies and carpenter ants, and to some extent against deer ticks. They may be applied to areas, locations and items which are desirably to be kept free of such insects, with applications being direct or of solutions or emulsions thereof, preferably by spraying, or in detergent compositions or other products to be applied to such areas, etc. Because the described neoalkanamides are desirably substantive to surfaces and are usually in liquid state, they give long lasting repellency to such areas, etc., and tests have shown them to be sufficiently long lasting.

  已发现 11 至 14 个碳原子的 N-单取代新烷酰胺，其中酰胺氮上的取代基为环状（芳香族或环脂肪族，如芳基或环烷基）且至少有 5 个碳原子，具有驱虫剂的作用，条件是任何芳香族取代基在正交位置上未被取代，并且当新烷酰基为新戊酰基时，N-环新烷酰胺中的碳原子总数至少为 12 个。这种新烷酰胺可用作蟑螂（包括美洲、德国和东方蟑螂）的驱避剂，对蚊子（包括按蚊和伊蚊）、黑蝇和木匠蚁也有效，在一定程度上对鹿蜱也有效。可将它们施用在希望没有此类昆虫的区域、地点和物品上，施用方式可以是直接施用，也可以是其溶液或乳液的施用，最好是通过喷洒，或在洗涤剂组合物或其他产品中施用到这些区域等。由于所述新烷酰胺对表面具有良好的吸附性，而且通常呈液态，因此它们对这些区域等具有持久的驱避作用，测试表明它们具有足够的持久性。
• ALLYL SULFIDE COMPOUNDS, AND COMPOSITIONS AND METHODS USING SAID COMPOUNDS FOR REPELLING BLOOD-FEEDING ARTHROPODS
  申请人：Contech Enterprises Inc.

  公开号：EP2142500B1

  公开（公告）日：2013-07-31
• COMPOUNDS, COMPOSITIONS AND METHODS FOR REPELLING BLOOD-FEEDING ARTHROPODS AND DETERRING THEIR LANDING AND FEEDING
  申请人：GRIES Regine M.

  公开号：US20090069407A1

  公开（公告）日：2009-03-12

  This invention relates to compositions of one or more compounds that incorporate one or more allyl sulfide, allyl disulfide or allyl polysulfide moieties, or one or more allyl sulfide, allyl disulfide or allyl polysulfide moieties and one or more hydroxyl groups, used in effective amount in formulations, including emulsions, to repel blood-feeding ectoparasitic arthropods, including mosquitoes, and to deter them from landing and feeding when applied to the skin, clothing or environment of animals, including humans. Said compounds can include, but are not limited to, 8-allyl-sulfanyloctan-1-ol. This invention also relates to compositions comprising one or more of said compounds in further combination with other arthropod repellent and deterrent compounds, including vanillin. These compounds may be formulated with inert ingredients to form a liquid, gel, paste, soap, spray, aerosol or powder.