cyclopenta-1,3-diene;1,3-dimethylnaphtho[2,1-c]chromene-6-thione;2-diphenylphosphanylethyl(diphenyl)phosphane;ruthenium(2+);tetrafluoroborate | 157620-35-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并呋喃类
• 英文名称: cyclopenta-1,3-diene;1,3-dimethylnaphtho[2,1-c]chromene-6-thione;2-diphenylphosphanylethyl(diphenyl)phosphane;ruthenium(2+);tetrafluoroborate
• CAS: 157620-35-4
• 化学式: BF₄*C₅₀H₄₃OP₂RuS
• 分子量: 941.779
• InChiKey: KARMUIXQWPQOBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.04
• 重原子数：
  60
• 可旋转键数：
  7
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  41.3
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  cyclopenta-1,3-diene;1,3-dimethylnaphtho[2,1-c]chromene-6-thione;2-diphenylphosphanylethyl(diphenyl)phosphane;ruthenium(2+);tetrafluoroborate 、 sodium thiomethoxide 以 丙酮 为溶剂， 以65%的产率得到
  参考文献：
  名称：

  Synthesis and ring-opening reactions of cationic ruthenium biaryl thionolactone complexes

  摘要：

  The preparations of novel thionolactone-bridged configuratively labile biaryls and their [Cp(R3P)2Ru]+-complexes are described. The dynamics of helimerization of these complexes and their reactivity towards nucleophiles have been investigated. Hydride transfer reagents lead to a cleavage of the thionolactone bridge to give the corresponding thiolate complexes, apparently via intermediate exothiolactolate ruthenium complexes. A similar lactolate analog is formed upon addition of a mild S-nucleophile.

  DOI：

  10.1016/0022-328x(94)80213-0
• 作为产物：
  描述：

  、 1,3-dimethyl-benzonaphtho<1,2-d>pyran-6-thione 以 二氯甲烷 为溶剂， 以98%的产率得到cyclopenta-1,3-diene;1,3-dimethylnaphtho[2,1-c]chromene-6-thione;2-diphenylphosphanylethyl(diphenyl)phosphane;ruthenium(2+);tetrafluoroborate
  参考文献：
  名称：

  Synthesis and ring-opening reactions of cationic ruthenium biaryl thionolactone complexes

  摘要：

  The preparations of novel thionolactone-bridged configuratively labile biaryls and their [Cp(R3P)2Ru]+-complexes are described. The dynamics of helimerization of these complexes and their reactivity towards nucleophiles have been investigated. Hydride transfer reagents lead to a cleavage of the thionolactone bridge to give the corresponding thiolate complexes, apparently via intermediate exothiolactolate ruthenium complexes. A similar lactolate analog is formed upon addition of a mild S-nucleophile.

  DOI：

  10.1016/0022-328x(94)80213-0

文献信息

• Atropo-Enantioselective Ring Cleavage of Lewis Acid Modified Biaryl Thionolactones^,
  作者：Gerhard Bringmann、Andreas Wuzik、Jörg Kümmel、Wolfdieter A. Schenk

  DOI：10.1021/om001040e

  日期：2001.4.1

  Attachment of an achiral, ruthenium-based Lewis acid fragment to configurationally unstable biaryl thionolactones 1a−1c, atropo-enantioselective reductive lactone cleavage of the resulting complexes with chiral hydride reagents, and subsequent decomplexation leads to axially chiral thioethers 3a−3c with enantiomeric ratios of up to 92:8.

  将非手性钌基路易斯酸片段连接到结构不稳定的联芳基硫代内酯1a - 1c上，将得到的配合物与手性氢化物试剂进行熵-对映选择性还原内酯裂解，随后的解聚导致具有对映体比率的轴向手性硫醚3a - 3c高达92：8。