4-Hydroxybutyl methyl butanedioate | 105674-87-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Hydroxybutyl methyl butanedioate
• 英文别名: 4-O-(4-hydroxybutyl) 1-O-methyl butanedioate
• CAS: 105674-87-1
• 化学式: C₉H₁₆O₅
• 分子量: 204.22
• InChiKey: MTGQSXHEWSMVPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  丁二酸二甲酯 生成 4-Hydroxybutyl methyl butanedioate
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Process For Purifying a Stream Comprising 1,4-Butanediol
  申请人：Reed Graham

  公开号：US20140350308A1

  公开（公告）日：2014-11-27

  A crude product stream of 1,4-butandiol and one or more of γ-butyrolactone, 2-(4-hydroxybutoxy)-tetrahydrofuran, 4-hydroxybutyl(4-hydroxybutyrate), and 3-(4-hydroxybutoxy)-tetrahydrofuran is supplied to a first distillation column. A side-draw of 1,4-butanediol and light components is removed, with the light components including at least some of those produced by reaction in the first distillation column. The stream is passed to a hydrogenation zone and subjected to hydrogenation in the presence of a hydrogenation catalyst. A 1,4-butanediol product stream having a reduced content of 2-(4-hydroxybutoxy)-tetrahydrofuran is recovered and passed to a second distillation column operated such that (4-hyroxybutyl)-4-hydroxybutyrate is removed as a bottom stream and a 1,4-butanediol stream is removed as overhead. The overhead stream removed is passed to a third distillation column and a purified 1,4-butanediol stream is recovered.

  一种粗品流包括1,4-丁二醇和一个或多个γ-丁内酯、2-(4-羟基丁氧基)-四氢呋喃、4-羟基丁酸丁酯和3-(4-羟基丁氧基)-四氢呋喃，被供给到第一蒸馏柱。1,4-丁二醇和轻组分的侧流被移除，其中轻组分包括至少一些在第一蒸馏柱中反应产生的组分。该流经过氢化区，并在氢化催化剂的存在下进行氢化。获得一种含有2-(4-羟基丁氧基)-四氢呋喃含量降低的1,4-丁二醇产品流，然后将其送入第二蒸馏柱，使得(4-羟基丁基)-4-羟基丁酸酯作为底部流和1,4-丁二醇流作为顶部流被移除。移除的顶部流经过第三蒸馏柱，获得纯化的1,4-丁二醇流。
• Process for purifying a stream comprising 1,4-butanediol
  申请人：Reed Graham

  公开号：US10322988B2

  公开（公告）日：2019-06-18

  A crude product stream of 1,4-butandiol and one or more of γ-butyrolactone, 2-(4-hydroxybutoxy)-tetrahydrofuran, 4-hydroxybutyl(4-hydroxybutyrate), and 3-(4-hydroxybutoxy)-tetrahydrofuran is supplied to a first distillation column. A side-draw of 1,4-butanediol and light components is removed, with the light components including at least some of those produced by reaction in the first distillation column. The stream is passed to a hydrogenation zone and subjected to hydrogenation in the presence of a hydrogenation catalyst. A 1,4-butanediol product stream having a reduced content of 2-(4-hydroxybutoxy)-tetrahydrofuran is recovered and passed to a second distillation column operated such that (4-hyroxybutyl)-4-hydroxybutyrate is removed as a bottom stream and a 1,4-butanediol stream is removed as overhead. The overhead stream removed is passed to a third distillation column and a purified 1,4-butanediol stream is recovered.

  由 1,4-丁二醇和γ-丁内酯、2-(4-羟基丁氧基)-四氢呋喃、4-羟基丁酸丁酯和 3-(4-羟基丁氧基)-四氢呋喃中的一种或多种组成的粗产品流被送入第一蒸馏塔。侧流的 1,4-丁二醇和轻组分被去除，其中轻组分至少包括在第一蒸馏塔中反应产生的部分轻组分。液流进入氢化区，在氢化催化剂的作用下进行氢化。回收的 1，4-丁二醇产品流中 2-(4-羟基丁氧基)-四氢呋喃的含量降低，并进入第二蒸馏塔，第二蒸馏塔的操作方式为：(4-羟基丁基)-4-羟基丁酸酯作为底流被除去，1，4-丁二醇作为顶流被除去。去除的顶流进入第三个蒸馏塔，回收纯化的 1,4-丁二醇流。
• ——
  作者：KOUBA J. K.、 ZLETZ A.

  DOI：——

  日期：——
• ZLETZ, ALEX
  作者：ZLETZ, ALEX

  DOI：——

  日期：——
• PROCESS FOR PURIFYING A STREAM COMPRISING 1,4-BUTANEDIOL
  申请人：Johnson Matthey Davy Technologies Limited

  公开号：EP2753597B1

  公开（公告）日：2018-10-17