2-(1,2-dimethyl-3-indolyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride | 126935-36-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-(1,2-dimethyl-3-indolyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride
• 英文别名: 3-(1,2-Dimethylindol-3-yl)-4-(2,4,5-trimethylthiophen-3-yl)furan-2,5-dione
• CAS: 126935-36-2
• 化学式: C₂₁H₁₉NO₃S
• 分子量: 365.453
• InChiKey: XVIJOYIXBCFJGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  76.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(1,2-dimethyl-3-indolyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride 以 苯 为溶剂， 生成 2,3,11,11a,11b-Pentamethyl-11a,11b-dihydro-11H-5-oxa-1-thia-11-aza-benzo[a]trindene-4,6-dione
  参考文献：
  名称：

  热不可逆光致变色系统。非对称二芳基乙烯衍生物的可逆光环化

  摘要：

  合成了一端为吲哚环、双键另一端为噻吩、苯并[b]噻吩或吡咯环的非对称二芳基乙烯，试图获得具有更长吸收带的热不可逆光致变色化合物波长。2-(1,2-Dimethyl-3-indoyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride(8a) 经历了光致环化/开环反应，量子产率相对较高（环化量子产率：0.15；开环量子产率：0.40），两种异构体都是热稳定的。闭环形式在 595 nm 处具有最大吸收，边缘延伸至 760 nm。8a 和 2-(1,2-二甲基-3-吲哚基)-3-(2-甲基-3-苯并[b]噻吩基)马来酸酐 (9a) 的环化/开环反应是由 Ar 离子诱导的 (488 nm) 和 He-Ne (633 nm) 激光器。

  DOI：

  10.1246/bcsj.64.789
• 作为产物：
  描述：

  2,3,11,11a,11b-Pentamethyl-11a,11b-dihydro-11H-5-oxa-1-thia-11-aza-benzo[a]trindene-4,6-dione 以 苯 为溶剂， 生成 2-(1,2-dimethyl-3-indolyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride
  参考文献：
  名称：

  热不可逆光致变色系统。非对称二芳基乙烯衍生物的可逆光环化

  摘要：

  合成了一端为吲哚环、双键另一端为噻吩、苯并[b]噻吩或吡咯环的非对称二芳基乙烯，试图获得具有更长吸收带的热不可逆光致变色化合物波长。2-(1,2-Dimethyl-3-indoyl)-3-(2,4,5-trimethyl-3-thienyl)maleic anhydride(8a) 经历了光致环化/开环反应，量子产率相对较高（环化量子产率：0.15；开环量子产率：0.40），两种异构体都是热稳定的。闭环形式在 595 nm 处具有最大吸收，边缘延伸至 760 nm。8a 和 2-(1,2-二甲基-3-吲哚基)-3-(2-甲基-3-苯并[b]噻吩基)马来酸酐 (9a) 的环化/开环反应是由 Ar 离子诱导的 (488 nm) 和 He-Ne (633 nm) 激光器。

  DOI：

  10.1246/bcsj.64.789

文献信息

• Reversible Fluorescence Photoswitch based on Dye-Crosslinked Dendritic Nanoclusters for High-Contrast Imaging of Living Biological Systems
  申请人：Kim Yoonkyung

  公开号：US20120220734A1

  公开（公告）日：2012-08-30

  The present invention relates to a reversible fluorescence photoswitch based on the dye-crosslinked dendritic nanoclusters for high-contrast imaging of living biological systems. The dendritic nanocluster according to the present invention consists of two or more dendrimers crosslinked each other to have a globular shape overall, and thereby enhancing the fluorescence intensity and improving the detection sensitivity of the monomeric dendrimers. In addition, the dendritic nanocluster according to the present invention was found to internalize into a living zebrafish by both skin permeation and microinjection, independently. Further, the dendritic nanocluster according to the present invention showed low toxicity and thus it could be useful for both in vivo and in vitro imaging as well as the ex vivo cell tracking applications.

  本发明涉及一种基于染料交联树状纳米团簇的可逆荧光光开关，用于高对比度成像活体生物系统。本发明的树状纳米团簇由两个或更多树状分子交联形成，整体呈球形，从而增强了单体树状分子的荧光强度并提高了检测灵敏度。此外，本发明的树状纳米团簇被发现可以通过皮肤渗透和微注射两种方式内化到活体斑马鱼中。此外，本发明的树状纳米团簇毒性低，因此可用于体内和体外成像以及细胞追踪应用。
• Optical recording medium
  申请人：SANYO ELECTRIC CO., LTD.

  公开号：EP0488153A1

  公开（公告）日：1992-06-03

  Disclosed herein is an optical recording medium comprising a recording layer containing a photochromic material and a polymer which are so combined with each other that a photostationary state attained upon irradiation with light of a specific wavelength is varied with temperatures, a reflective layer for reflecting light which is passed through the recording layer, and a substrate for supporting a laminate of the recording layer and the reflective layer. The use of a diarylethene derivative as photochromic material is disclosed.

  本文公开了一种光学记录介质，该介质包括一个记录层，其中含有一种光致变色材料和一种聚合物，这两种材料相互结合，在特定波长的光照射下达到的光静止状态随温度而变化；一个反射层，用于反射穿过记录层的光线；以及一个基板，用于支撑记录层和反射层的层压板。公开了一种二芳基噻吩衍生物作为光致变色材料的用途。
• Recording/reproducing method for optical recording medium
  申请人：SANYO ELECTRIC CO., LTD.

  公开号：EP0495185A2

  公开（公告）日：1992-07-22

  Disclosed herein is a recording/reproducing method for an optical recording medium comprising a step of heating a recording layer containing a photochromic material and a polymer which are so combined with each other that a photostationary state attained upon irradiation with light of a specific wavelength is varied with temperatures, and a step of applying the light of a specific wavelength to the heated recording layer for bringing the same into a photostationary state and recording information. In order to reproduce the information, a portion of the recording layer which is in a photostationary state is selectively heated, and reproducing light is applied to reproduce recorded and unrecorded states.

  本文公开了一种光学记录介质的记录/复制方法，该方法包括加热记录层的步骤，该记录层含有光致变色材料和聚合物，这两种材料相互结合，在特定波长的光照射下达到的光静止状态随温度变化；以及将特定波长的光照射到加热的记录层上，使其进入光静止状态并记录信息的步骤。为了再现信息，有选择地加热处于光静止状态的记录层的一部分，并施加再现光以再现已记录和未记录的状态。
• Lithographic printing plate precursor and lithographic printing method
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP1754614A1

  公开（公告）日：2007-02-21

  The invention is directed to a lithographic printing plate precursor comprising a support and an image-recording layer, wherein the image-recording layer comprises (1) an infrared absorber and (2) a photochromic compound. The invention is also directed to a method of plate making and a lithographic printing method, each method using the lithographic printing plate precursor.

  本发明涉及一种平版印刷板前体，包括一个支撑物和一个图像记录层，其中图像记录层包括(1)红外线吸收剂和(2)光致变色化合物。本发明还涉及一种制版方法和一种平版印刷方法，每种方法都使用平版印刷板前体。
• TIME-TEMPERATURE INDICATOR BASED ON VALENCE ISOMERIZATIONS
  申请人：FRESHPOINT HOLDINGS SA

  公开号：EP1711809A2

  公开（公告）日：2006-10-18