dimethyl 2-chloro-2,4,4-trimethylglutarate | 213246-94-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dimethyl 2-chloro-2,4,4-trimethylglutarate
• 英文别名: H-(MMA)_2-Cl；Pentanedioic acid, 2-chloro-2,4,4-trimethyl-, dimethyl ester；dimethyl 2-chloro-2,4,4-trimethylpentanedioate
• CAS: 213246-94-7
• 化学式: C₁₀H₁₇ClO₄
• 分子量: 236.696
• InChiKey: WTGGMKXPQIAQNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,4-dimethoxyacetophenone trimethylsilyl enol ether 、 dimethyl 2-chloro-2,4,4-trimethylglutarate 在 2,2'-联吡啶 、 copper(l) chloride 作用下， 以 二甲基亚砜 为溶剂， 以69 %的产率得到dimethyl 2-(2-(2,4-dimethoxyphenyl)-2-oxoethyl)-2,4,4-trimethylpentanedioate
  参考文献：
  名称：

  Sulfur‐Free Radical RAFT Polymerization of Methacrylates in Homogeneous Solution: Design of exo ‐Olefin Chain‐Transfer Agents (R−CH ₂ C(=CH ₂ )Z)

  摘要：

  AbstractIn this work, the development of exo‐olefin compounds (R−CH2C(=CH2)Z) as chain‐transfer agents for the sulfur‐free reversible addition‐fragmentation chain transfer (RAFT) radical polymerization of methacrylates in homogeneous solution is described. A series of exo‐olefin compounds with a methyl methacrylate (MMA) dimer structure as the R group and a substituted α‐methylstyrene unit as the −CH2C(=CH2)Z (Z: Ph−Y) group were synthesized and used for the radical polymerization of MMA in toluene and PhC(CF3)2OH. These compounds underwent transfer of the CH2C(=CH2)Z group via addition‐fragmentation of the propagating methacryloyl radical. More electron‐donating (Y) substituents, such as methoxy and dimethylamino groups, produced polymers with narrower molecular weight distributions. A continuous monomer addition method further improved molecular weight control and enabled the synthesis of colorless, sulfur‐free, multiblock copolymers of methacrylates in homogeneous solutions.

  DOI：

  10.1002/anie.202212633

文献信息

• Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer
  申请人：Uemura Makoto

  公开号：US20070270521A1

  公开（公告）日：2007-11-22

  A transition metal compound represented by the formula, [(CpR 1 m )(CO) 2 M 1 ][M 2 (CO) 2 (CpR 2 n )], wherein Cp is a cyclopentadienyl ring, R 1 and R 2 are independently of each other a hydrocarbyl group having 1 to 20 carbon atoms, and each of at least one R 1 and at least one R 2 is a hydrocarbyl group having 5 to 20 carbon atoms, m and n are independently of each other an integer of 1 to 5, and M 1 and M 2 are independently of each other a transition metal atom of the group 8 in the periodic table of elements; a polymerization-initiator system comprising said transition metal compound; and a process for producing a polymer in the presence of the polymerization-initiator system.

  一个由该公式表示的过渡金属化合物，[(CpR1m)(CO)2M1][M2(CO)2(CpR2n)]，其中Cp是一个环戊二烯环，R1和R2是独立的烃基团，含有1至20个碳原子，至少一个R1和至少一个R2是含有5至20个碳原子的烃基团，m和n是独立的1至5的整数，M1和M2是元素周期表中8族的过渡金属原子；包括所述过渡金属化合物的聚合物化引发剂系统；以及在聚合物化引发剂系统存在的情况下生产聚合物的过程。
• Metal complexes useful in metathesis and other reactions
  申请人：Walter Francis

  公开号：US20050043541A1

  公开（公告）日：2005-02-24

  This invention provides metal complexes being useful as catalyst components in metathesis reactions and in reactions involving the transfer of an atom or group to an ethylenically or acetylenically unsaturated compound or another reactive substrate and, with respect to a sub-class thereof, for the polymerisation of α-olefins and optionally conjugated dienes, with high activity at moderate tempera-tures. It also provides methods for obtaining polymers with very narrow molecular weight distribution by means of a living reaction. It also provides methods for making said metal complexes and novel intermediates involved in such methods. It further provides derivatives of said metal complexes which are suitable for covalent bonding to a carrier, the product of such covalent bonding being useful as a supported catalyst for heterogeneous catalytic reactions. It also provides a direct one-step synthesis of pyrrole, furan and thiophene compounds from diallyl compounds.

  本发明提供了金属配合物，可用作交换反应中的催化剂组分，以及涉及将原子或基团转移至乙烯基或乙炔基不饱和化合物或其他反应底物的反应中，并且针对其亚类别，用于α-烯烃和可选的共轭二烯的聚合，具有在中等温度下高活性。它还提供了通过活性反应获得非常窄的分子量分布的聚合物的方法。它还提供了制备该金属配合物和涉及这种方法的新型中间体的方法。它还提供了该金属配合物的衍生物，适用于与载体进行共价键合，该共价键合的产物可用作异相催化反应的支持催化剂。它还提供了从双烯基化合物直接合成吡咯、呋喃和噻吩化合物的一步法。
• Metal complexes for use in olefin methathesis and atom or group transfer reactions
  申请人：UNIVERSITEIT GENT

  公开号：EP1577282A2

  公开（公告）日：2005-09-21

  Improved catalysts useful in a number of organic synthesis reactions such as olefin metathesis and atom or group transfer reactions are made by bringing into contact a multi-coordinated metal complex comprising a multidentate Schiff base ligand, and one or more other ligands, with an acid under conditions such that said acid is able to at least partly cleave a bond between the metal and the multidentate Schiff base ligand of said metal complex, optionally through intermediate protonation of said Schiff base ligand.

  在烯烃复分解反应和原子或基团转移反应等一系列有机合成反应中使用的改良催化剂，是通过将包含多叉席夫碱配体和一个或多个其他配体的多配位金属络合物与酸接触而制成的，接触条件是所述酸能够至少部分裂解金属与所述金属络合物的多叉席夫碱配体之间的键，还可选择通过所述席夫碱配体的中间质子化。
• RADIATION-SENSITIVE RESIN COMPOSITION
  申请人：JSR Corporation

  公开号：EP1602975A1

  公开（公告）日：2005-12-07

  A radiation-sensitive resin composition comprising an acid-labile group-containing resin obtained by living radical polymerization having a specific structure which is insoluble or scarcely soluble in alkali, but becomes alkali soluble by the action of an acid, and a photoacid generator, wherein the ratio of weight average molecular weight to number average molecular weight (weight average molecular weight/number average molecular weight) of the acid-labile group-containing-resin is smaller than 1.5.

  一种辐射敏感树脂组合物，包括一种通过活自由基聚合获得的具有特定结构的含酸基团树脂，该树脂不溶于碱或几乎不溶于碱，但在酸的作用下可溶于碱，还包括一种光酸发生器，其中含酸基团树脂的重量平均分子量与数量平均分子量之比（重量平均分子量/数量平均分子量）小于 1.5。
• Polymer, a method for producing the polymer, and a cement admixture using the same
  申请人：NIPPON SHOKUBAI CO., LTD.

  公开号：EP1767564A2

  公开（公告）日：2007-03-28

  To provide a polymer having a specific parameter value with a very narrow molecular weight distribution different from the conventional copolymers despite of a polymer having a polyoxyalkylene chain, and an excellent dispersant for inorganic powders, particularly a cement addmixture. The polymer (P) in the present invention is containing a constitutional unit derived from a polyoxyalkylene chain, and satisfying a range of PD value defined as the following mathematical formula 1: 1

  本发明的目的是提供一种聚合物，该聚合物具有不同于传统共聚物的特定参数值和非常窄 的分子量分布，尽管该聚合物具有聚氧亚烷基链，但该聚合物是无机粉末，特别是水泥添加混 合物的优良分散剂。本发明中的聚合物（P）含有由聚氧亚烷基链衍生的构型单元，并满足如下数学公式 1 所定义的 PD 值范围： 1