motrilin | 138551-27-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: motrilin
• 英文别名: 4-[(13R)-13-[(2R,5R)-5-[(2R,5R)-5-[(1S)-1,6-dihydroxyundecyl]oxolan-2-yl]oxolan-2-yl]-13-hydroxytridecyl]-2-methyl-2H-furan-5-one
• CAS: 138551-27-6
• 化学式: C₃₇H₆₆O₇
• 分子量: 622.927
• InChiKey: XZNOZEYKFBKGEY-YXJOTKONSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  44
• 可旋转键数：
  25
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  motrilin 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成 2,33-dihydromotrilin
  参考文献：
  名称：

  Molvizarin and motrilin: Two novel cytotoxic bis-tetrahydro-furanic γ-lactone acetogenins from Annona cherimolia

  摘要：

  Two new cytotoxic adjacent bis-tetrahydrofuranic acetogenins, molvizarin and motrilin, have been isolated from the cytotoxic methanolic extract of Annona cherimolia seeds. Their structures were established on the basis of 2D-NMR spectroscopic techniques. While molvizarin (1) belongs to the very rare type of C35bis-tetrahydrofuranic acetogenins, motrilin (2) is the first example of a C-29 hydroxylated acetogenin.

  DOI：

  10.1016/s0040-4020(01)91014-2

文献信息

• Molvizarin and motrilin: Two novel cytotoxic bis-tetrahydro-furanic γ-lactone acetogenins from Annona cherimolia
  作者：Diego Cortes、Saw H. Myint、Reynald Hocquemiller

  DOI：10.1016/s0040-4020(01)91014-2

  日期：1991.9

  Two new cytotoxic adjacent bis-tetrahydrofuranic acetogenins, molvizarin and motrilin, have been isolated from the cytotoxic methanolic extract of Annona cherimolia seeds. Their structures were established on the basis of 2D-NMR spectroscopic techniques. While molvizarin (1) belongs to the very rare type of C35bis-tetrahydrofuranic acetogenins, motrilin (2) is the first example of a C-29 hydroxylated acetogenin.