Teucrolivin G | 134885-92-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并呋喃类
• 英文名称: Teucrolivin G
• 英文别名: [(1S,5R,6R,7S,9S,11S,13S)-7-acetyloxy-11-(furan-3-yl)-9,13-dimethyl-4-oxospiro[10,14-dioxatetracyclo[9.2.1.01,6.09,13]tetradecane-5,2'-oxirane]-6-yl]methyl acetate
• CAS: 134885-92-0
• 化学式: C₂₄H₂₈O₉
• 分子量: 460.481
• InChiKey: PVDDMXMYNHAGMK-DAMCVVMBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  114
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  乙酸酐 、 Teucrolivin H 在 吡啶 作用下， 反应 48.0h， 生成 Teucrolivin G
  参考文献：
  名称：

  Two neo-clerodane diterpenoids containing an unusual 2,6-dioxabicyclo[2.2.1]heptane structural moiety

  摘要：

  Two new diterpenoids, teucrolivins G and H, have been isolated from the aerial parts of Teucrium oliverianum (Labiatae). The structures of teucrolivin G [6-alpha,19-diacetoxy-4-alpha,18;15,16-diepoxy-3-oxo-neo-cleroda-13(16), 14-dien-12,8-beta,10-beta-acetal, 1] and teucrolivin H [19-acetoxy-4-alpha,18;15,16-diepoxy-6-alpha-hydroxy-3-oxo-neo-cleroda-13(16),14-dien-12,8-beta,10-beta-acetal, 2] were established mainly by spectroscopic means, including an x-ray diffraction analysis of the former (1). Compounds 1 and 2 possess an unusual 2,6-dioxabicyclo [2.2.1] heptane structural moiety which, to the best of our knowledge, has now been found for the first time in natural products.

  DOI：

  10.1016/s0040-4020(01)86408-5