O-(2-hydroxy-phenyl)-tyrosine | 4732-84-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: O-(2-hydroxy-phenyl)-tyrosine
• 英文别名: 4-(2-Hydroxy-phenoxy)-DL-phenylalanin；O-(2-Hydroxy-phenyl)-tyrosin；2-Amino-3-[4-(2-hydroxyphenoxy)phenyl]propanoic acid
• CAS: 4732-84-7
• 化学式: C₁₅H₁₅NO₄
• 分子量: 273.288
• InChiKey: OLNYQXHRTWKIQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  92.8
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  乙酸酐 、 alkaline earth salt of/the/ methylsulfuric acid 在 磷化氢 、 氢碘酸 作用下， 生成 O-(2-hydroxy-phenyl)-tyrosine
  参考文献：
  名称：

  The Synthesis of dl-“Ortho”-Thyronine¹

  摘要：

  DOI：

  10.1021/ja01853a018

文献信息

• BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES
  申请人：Kohn Joachim B.

  公开号：US20120226013A1

  公开（公告）日：2012-09-06

  The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.

  本发明涉及新型单体化合物，可以聚合形成新颖的可生物降解和可生物吸收的聚合物和共聚物。这些聚合物和共聚物，虽然不限于此，可以适用于放射透明度，并且适用于医疗器械应用和控释治疗制剂。
• BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES
  申请人：Rutgers, The State University of New Jersey

  公开号：EP3461855A1

  公开（公告）日：2019-04-03

  The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.

  本发明涉及新型单体化合物，可通过聚合形成新型可生物降解和可生物复原的聚合物和共聚物。这些聚合物和共聚物虽然并不局限于此，但可具有放射性能力，可用于医疗器械应用和控释治疗制剂。
• Biocompatible polymers for medical devices
  申请人：Rutgers, The State University of New Jersey

  公开号：US10202490B2

  公开（公告）日：2019-02-12

  The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.

  本发明涉及新型单体化合物，可通过聚合形成新型可生物降解和可生物复原的聚合物和共聚物。这些聚合物和共聚物虽然并不局限于此，但可具有放射性能力，可用于医疗器械应用和控释治疗制剂。
• US9605112B2
  申请人：——

  公开号：US9605112B2

  公开（公告）日：2017-03-28
• [EN] BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES<br/>[FR] POLYMÈRES BIOCOMPATIBLES POUR DISPOSITIFS MÉDICAUX
  申请人：UNIV RUTGERS

  公开号：WO2011044567A1

  公开（公告）日：2011-04-14

  The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.