5,23-Dimethoxy-14-[2-(1,4,7,10-tetrazacyclododec-1-yl)ethyl]-14-azahexacyclo[15.8.0.02,11.03,8.012,16.020,25]pentacosa-1(17),2(11),3(8),4,6,12(16),20(25),21,23-nonaene-13,15-dione | 1366018-34-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 5,23-Dimethoxy-14-[2-(1,4,7,10-tetrazacyclododec-1-yl)ethyl]-14-azahexacyclo[15.8.0.02,11.03,8.012,16.020,25]pentacosa-1(17),2(11),3(8),4,6,12(16),20(25),21,23-nonaene-13,15-dione
• CAS: 1366018-34-9
• 化学式: C₃₆H₄₃N₅O₄
• 分子量: 609.769
• InChiKey: YGXNAHGURPEDBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  45
• 可旋转键数：
  5
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  95.2
• 氢给体数：
  3
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  Tritert-butyl 10-[2-(5,23-dimethoxy-13,15-dioxo-14-azahexacyclo[15.8.0.02,11.03,8.012,16.020,25]pentacosa-1(17),2(11),3(8),4,6,12(16),20(25),21,23-nonaen-14-yl)ethyl]-1,4,7,10-tetrazacyclododecane-1,4,7-tricarboxylate 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 生成 5,23-Dimethoxy-14-[2-(1,4,7,10-tetrazacyclododec-1-yl)ethyl]-14-azahexacyclo[15.8.0.02,11.03,8.012,16.020,25]pentacosa-1(17),2(11),3(8),4,6,12(16),20(25),21,23-nonaene-13,15-dione
  参考文献：
  名称：

  Turn-On Fluorescent Sensor for Selective Detection of Zn²⁺, Cd²⁺, and Hg²⁺ in Water

  摘要：

  A new fluorescent chemosensor based on a helical imide as fluorophore and a cyclen moiety as ionophore was synthesized, which not only showed enhanced fluorescent responses in the presence of Zn2+, Cd2+, and Hg2+ but also could simultaneously and selectively distinguish the three cations in a simulated physiological condition with the help of cysteine as an auxiliary reagent.

  DOI：

  10.1021/jo3002744

文献信息

• Turn-On Fluorescent Sensor for Selective Detection of Zn²⁺, Cd²⁺, and Hg²⁺ in Water
  作者：Meng Li、Hai-Yan Lu、Rui-Li Liu、Jun-Dao Chen、Chuan-Feng Chen

  DOI：10.1021/jo3002744

  日期：2012.4.6

  A new fluorescent chemosensor based on a helical imide as fluorophore and a cyclen moiety as ionophore was synthesized, which not only showed enhanced fluorescent responses in the presence of Zn2+, Cd2+, and Hg2+ but also could simultaneously and selectively distinguish the three cations in a simulated physiological condition with the help of cysteine as an auxiliary reagent.