7-methyl-2-octenoyl chloride | 1258519-41-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 7-methyl-2-octenoyl chloride
• 英文别名: (E)-7-methyloct-2-enoyl chloride
• CAS: 1258519-41-3
• 化学式: C₉H₁₅ClO
• 分子量: 174.671
• InChiKey: UNXRTFVZJMPQSP-FNORWQNLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  7-methyl-2-octenoyl chloride 、 [5-[(2-Methylpropan-2-yl)oxycarbonylamino]pentylamino] benzoate 在 过氧化苯甲酰 作用下， 以 二氯甲烷 为溶剂， 反应 19.0h， 以3.5 g的产率得到(E)-N-Boc-N'-benzoyloxy-N'-(7'-methyl-2'-octenoyl)-cadaverine
  参考文献：
  名称：

  Synthesis and biological activities of flavolipids

  摘要：

  Syntheses of the bacterial surfactants 6S 6S- 9S 9S- and 9U 9U-flavolipids confirmed the structures proposed for them from spectroscopic analysis of a flavolipid mixture and made pure flavolipids available for the first time All three synthetic flavolipids and a straight chain analogue were found to be weakly cytotoxic and to inhibit metastatic cancer cell migration with 9U 9U-fiavolipid (the most abundant natural flavolipid) having the most activity Biosynthetic routes to the branched side-chains of the flavolipids are suggested and it is proposed that branched chains are employed to hinder biodegradation (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tet.2010.09.088
• 作为产物：
  描述：

  (E)-7-methyl-2-octenoic acid 在 草酰氯 、 N,N-二甲基甲酰胺 作用下， 以 苯 为溶剂， 反应 0.5h， 生成 7-methyl-2-octenoyl chloride
  参考文献：
  名称：

  Synthesis and biological activities of flavolipids

  摘要：

  Syntheses of the bacterial surfactants 6S 6S- 9S 9S- and 9U 9U-flavolipids confirmed the structures proposed for them from spectroscopic analysis of a flavolipid mixture and made pure flavolipids available for the first time All three synthetic flavolipids and a straight chain analogue were found to be weakly cytotoxic and to inhibit metastatic cancer cell migration with 9U 9U-fiavolipid (the most abundant natural flavolipid) having the most activity Biosynthetic routes to the branched side-chains of the flavolipids are suggested and it is proposed that branched chains are employed to hinder biodegradation (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tet.2010.09.088