1-Acetoxy-2,4-dihydroxy-heptadecan | 25346-16-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-Acetoxy-2,4-dihydroxy-heptadecan
• 英文别名: 2,4-Dihydroxyheptadecyl acetate
• CAS: 25346-16-1
• 化学式: C₁₉H₃₈O₄
• 分子量: 330.508
• InChiKey: ZBVKFVTUHVIICH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-Acetoxy-2,4-dihydroxy-heptadecan 在 chromium(VI) oxide 作用下， 以 乙醚 为溶剂， 生成 1-Acetoxy-2-hydroxy-4-oxo-heptadecan
  参考文献：
  名称：

  New compounds from avocado pear

  摘要：

  DOI：

  10.1016/s0040-4020(01)83005-2
• 作为产物：
  描述：

  avocadyne acetate 在 钯 氢气 作用下， 以 乙醚 为溶剂， 生成 1-Acetoxy-2,4-dihydroxy-heptadecan
  参考文献：
  名称：

  New compounds from avocado pear

  摘要：

  DOI：

  10.1016/s0040-4020(01)83005-2

文献信息

• COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND THE THERAPEUTIC USES
  申请人：Meretzki, Shai

  公开号：EP2334293A2

  公开（公告）日：2011-06-22
• THERAPEUTIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND USES THEREOF
  申请人：Meretzki Shai

  公开号：US20110217251A1

  公开（公告）日：2011-09-08

  Therapeutic compositions comprising pharmaceutically effective amounts of isolated polyhydroxylated fatty alcohols, in particular suitable for topical or systemic administration. A method for the isolation of a natural polyhydroxylated fatty alcohol from a fruit or vegetable source is also disclosed.
• Chemosensory Receptor Ligand-Based Therapies
  申请人：Baron Alain D.

  公开号：US20130281387A1

  公开（公告）日：2013-10-24

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
• [EN] COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND THE THERAPEUTIC USES<br/>[FR] COMPOSITIONS COMPRENANT DES DÉRIVÉS D'ALCOOLS GRAS POLYHYDROXYLÉS, ET LEURS UTILISATIONS À DES FINS THÉRAPEUTIQUES
  申请人：MERETZKI SHAI

  公开号：WO2010026596A2

  公开（公告）日：2010-03-11

  Therapeutic compositions comprising pharmaceutically effective amounts of isolated polyhydroxylated fatty alcohols, in particular suitable for topical or systemic administration. A method for the isolation of a natural polyhydroxylated fatty alcohol from a fruit or vegetable source is also disclosed.
• [EN] CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES<br/>[FR] THÉRAPIES BASÉES SUR UN LIGAND DE RÉCEPTEUR CHIMIOSENSORIEL
  申请人：ELCELYX THERAPEUTICS INC

  公开号：WO2012054528A2

  公开（公告）日：2012-04-26

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.