5-(1-Hydroxy-ethyl)-1,7-dimethyl-9,10-dihydro-phenanthrene-2,6-diol

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 5-(1-Hydroxy-ethyl)-1,7-dimethyl-9,10-dihydro-phenanthrene-2,6-diol
• 英文别名: 5-(1-Hydroxyethyl)-1,7-dimethyl-9,10-dihydrophenanthrene-2,6-diol
• 化学式: C₁₈H₂₀O₃
• 分子量: 284.355
• InChiKey: FXSNGZRFJOQOMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-acetyl-2,6-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene 在 lithium aluminium tetrahydride 作用下， 生成 5-(1-Hydroxy-ethyl)-1,7-dimethyl-9,10-dihydro-phenanthrene-2,6-diol
  参考文献：
  名称：

  Cytotoxic 9,10-Dihydrophenanthrenes from Juncus effusus L.

  摘要：

  Nine 9,10-dihydrophenanthrenes, seven of them described for the first time, have been isolated in a further investigation of Juncus effusus. The structures have been defined on the basis of the spectral properties of the compounds. All the dehydrophenanthrene metabolites present in the plant have been tested for their cytotoxic properties and many of them have been found to have a good in vitro activity.

  DOI：

  10.1016/s0040-4020(01)90169-3