3,5,4'-trihydroxy-6,7-methylenedioxyflavone | 70610-25-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,5,4'-trihydroxy-6,7-methylenedioxyflavone
• 英文别名: Gomphrenol；7,9-dihydroxy-6-(4-hydroxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one
• CAS: 70610-25-2
• 化学式: C₁₆H₁₀O₇
• 分子量: 314.251
• InChiKey: WBQNGHIOSSPSDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3,5,4'-trihydroxy-6,7-methylenedioxy-3-O-β-D-glucopyranoside 在 盐酸 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 3.0h， 以66 mg的产率得到3,5,4'-trihydroxy-6,7-methylenedioxyflavone
  参考文献：
  名称：

  Flavonoid glucosides from Polygonum tinctorium.

  摘要：

  A new flavonoid-glucoside, 3, 5, 4'-trihydroxy-6, 7-methylenedioxy-3-O-β-D-glucopyranoside, which has an anti-platelet activity, was isolated from Polygonum tinctorium LOUR. and its structure was elucidated by means of carbon-13 nuclear magnetic resonance, including long range selective-proton decoupling (LSPD), and other spectroscopic methods.

  DOI：

  10.1248/cpb.38.523

文献信息

• Physiologically active extract
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0987027A1

  公开（公告）日：2000-03-22

  A physiologically active extract comprising an ethyl acetate-soluble ingredient of an indigo plant, which is obtainable by soaking a raw indigo plant in an organic solvent used for extraction. The ethyl acetate-soluble ingredient includes tryptanthrin, 3,5,4'-trihydroxy-6,7-methylenedioxy-flavone, kaempferol, 3,5,7,4'-tetrahydroxy-6-methoxy-flavone, gallic acid, caffeic acid, indirubin, pheophorbide a, and methylpheophorbide a.

  一种含有靛蓝植物乙酸乙酯可溶性成分的生理活性提取物，可通过将未加工的靛蓝植物浸泡在用于提取的有机溶剂中获得。乙酸乙酯可溶性成分包括胰黄素、3,5,4'-三羟基-6,7-亚甲二氧基-黄酮、山柰酚、3,5,7,4'-四羟基-6-甲氧基-黄酮、没食子酸、咖啡酸、靛红素、雉肽 a 和甲基雉肽 a。
• PHYSIOLOGICALLY ACTIVE EXRACT
  申请人：——

  公开号：US20020068094A1

  公开（公告）日：2002-06-06

  A physiologically active extract comprising an ethyl acetate-soluble ingredient of an indigo plant, which is obtainable by soaking a raw indigo plant in an organic solvent used for extraction. The ethyl acetate-soluble ingredient includes tryptanthrin, 3,5,4′-trihydroxy-6,7-methylenedioxy-flavone, kaempferol, 3,5,7,4′-tetrahydroxy-6-methoxy-flavone, gallic acid, caffeic acid, indirubin, pheophorbide a, and methylpheophorbide a.

  一种含有靛蓝植物乙酸乙酯可溶性成分的生理活性提取物，可通过将未加工的靛蓝植物浸泡在用于提取的有机溶剂中获得。乙酸乙酯可溶性成分包括胰黄素、3,5,4′-三羟基-6,7-亚甲二氧基-黄酮、山柰酚、3,5,7,4′-四羟基-6-甲氧基-黄酮、没食子酸、咖啡酸、靛红素、嗜铬甙 a 和甲基嗜铬甙 a。
• KANDA, XIROSI;ITO, XIROSI
  作者：KANDA, XIROSI、ITO, XIROSI

  DOI：——

  日期：——
• Ethyl acetate extract from Indigo plant
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0987027B1

  公开（公告）日：2004-08-11
• US6524625B2
  申请人：——

  公开号：US6524625B2

  公开（公告）日：2003-02-25