顺十五碳-10-烯酸 | 84743-29-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 顺十五碳-10-烯酸
• 中文别名: 10C-十五烯酸；顺十五碳-1-烯酸
• 英文名称: cis-10-pentadecenoic acid
• 英文别名: 10(Z)-pentadecenoic acid；10Z-pentadecenoic acid；(Z)-pentadec-10-enoic acid
• CAS: 84743-29-3
• 化学式: C₁₅H₂₈O₂
• 分子量: 240.386
• InChiKey: APXSAEQXOXTDAM-WAYWQWQTSA-N

物化性质

• 沸点：
  321.9±11.0 °C(Predicted)
• 密度：
  0.909±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2916190090

反应信息

• 作为反应物：
  描述：

  顺十五碳-10-烯酸 在 ammonium hydroxide 、 草酰氯 作用下， 以 乙醚 、 正己烷 为溶剂， 反应 0.5h， 生成 (Z)-Pentadec-10-enoic acid amide
  参考文献：
  名称：

  Primary Tetradecenyl Amines from the Ant Monomorium floricola

  摘要：

  In contrast to other ants in the genus Monomorium that produce cyclic amines, extracts of Monomorium floricola contain (Z)-7-tetradecenylamine (1) and (Z)-9-tetradecenylamine (2). The structures of these compounds were established from their spectral data and by comparison with synthetic 2.

  DOI：

  10.1021/np960350s

文献信息

• Different roles for the acyl chain and the amine leaving group in the substrate selectivity of <i>N</i>-Acylethanolamine acid amidase
  作者：Andrea Ghidini、Laura Scalvini、Francesca Palese、Alessio Lodola、Marco Mor、Daniele Piomelli

  DOI：10.1080/14756366.2021.1912035

  日期：2021.1.1

  length is still lacking. In this report, we combined enzymatic and molecular modelling approaches to determine the effects of acyl chain and polar head modifications on substrate recognition and hydrolysis by NAAA. The results show that, in both saturated and monounsaturated FAEs, the catalytic efficiency is strictly dependent upon fatty acyl chain length, whereas there is a wider tolerance for modifications

  摘要 N-酰基乙醇胺酸酰胺酶 (NAAA) 是一种N-末端亲核试剂 (Ntn) 水解酶催化内源性镇痛和抗炎剂棕榈酰乙醇酰胺 (PEA) 的细胞内失活。NAAA 抑制剂可以抵消这一过程，并在疼痛、炎症和神经退行性疾病的动物模型中发挥显着的治疗作用。虽然已知 NAAA 优先水解饱和脂肪酸乙醇酰胺 (FAE)，但仍缺乏催化效率与脂肪酸链长度之间关系的详细概况。在本报告中，我们结合酶促和分子建模方法来确定酰基链和极性头部修饰对 NAAA 底物识别和水解的影响。结果表明，在饱和和单不饱和 FAE 中，催化效率严格取决于脂肪酰基链长，而对极头的修改有更广泛的容忍度。这种关系反映了酶-底物复合物在分子动力学模拟中的相对稳定性。
• GC-FID analysis of fatty acids and biological activity of Zanthoxylum rhetsa seed oil
  作者：Rajashri Naik

  DOI：10.13005/ojc/310409

  日期：2015.12.30

  The Fatty acid content and composition of fixed oil from Zanthoxylum rhetsa seeds was determined. The seeds were found to contain about ~19.5% of crude fixed oil on a dry weight basis. Fatty acids were converted into methyl esters and analyzed by GC-FID. Ten fatty acids were identified using GC-FID. The major monounsaturated and saturated fatty acids were oleic acid (41.6 - 43.5%) and palmitic acid (26.8-30.2%) respectively, whereas the α-linolenic acid (12.1 - 12.5%) and linoleic acid (10.0%) were polyunsaturated fatty acid. Stearic acid (5.2 - 6.0%), myristic acid (0.1%), traces of pentadecanoic, heptadecanoic and arachidic acid were also identified. These fatty acids have not been reported earlier from the oil of Z. rhetsa. Fixed oil exhibited significant free radical scavenging activity which was measured using DPPH, and is also known to inhibit the gastrointestinal motility significantly.

  从香椒种子中提取的固定油的脂肪酸含量和组成被确定。研究发现，这些种子在干重基础上含有约19.5%的粗固定油。脂肪酸被转化为甲酯，并通过气相色谱-氢火焰离子化检测器（GC-FID）进行分析。通过GC-FID鉴定了十种脂肪酸。主要的单不饱和和饱和脂肪酸分别为油酸（41.6 - 43.5%）和棕榈酸（26.8 - 30.2%），而α-亚麻酸（12.1 - 12.5%）和亚油酸（10.0%）则为多不饱和脂肪酸。此外，还鉴定了硬脂酸（5.2 - 6.0%）、肉豆蔻酸（0.1%）以及微量的十五酸、十七酸和花生酸。这些脂肪酸以前未在香椒油中报道。固定油表现出显著的清除自由基活性，通过DPPH测量，并且还被知晓显著抑制胃肠道运动能力。
• Algal extracts comprising fucoxanthin and fucoxanthinol
  申请人：Greenaltech S.L.

  公开号：EP2918278A1

  公开（公告）日：2015-09-16

  The invention relates to an algal extract comprising fucoxanthin and fucoxanthinol, its production process, and the use thereof in cosmetic, cosmeceutical, food, nutraceutical, or pharmaceutical applications.

  本发明涉及一种含有岩藻黄素和岩藻黄素醇的藻类提取物、其生产工艺以及在化妆品、药妆、食品、营养保健品或药品中的应用。
• Chitin and chitosan producing methods
  申请人：Greenaltech, S.L.

  公开号：EP3034612A1

  公开（公告）日：2016-06-22

  The invention relates to the field of polymer production, in particular to the production of chitin and chitosan from microalgae belonging to the phylum Haptophyta to the phylum Chlorophyta, or to the phylum Heterokontophyta, particularly from microalgae of the genus Isochrysis, Chlorella, Bracteacoccus, Chlorococcum, Scenedesmus, Dunaliella, Haematococcus, Thalassiosira and Nannochloropsis, as well as to microalgal extracts thereof and their uses.

  本发明涉及聚合物生产领域，特别是用属于甲壳纲、叶绿藻纲或异叶绿藻纲的微藻生产甲壳素和壳聚糖、特别是从等绿藻属（Isochrysis）、小球藻属（Chlorella）、白术属（Bracteacoccus）、绿球藻属（Chlorococcum）、景天属（Scenedesmus）、盾叶藻属（Dunaliella）、血球藻属（Haematococcus）、褐藻属（Thalassiosira）和褐藻属（Nannochloropsis）的微藻中提取甲壳素和壳聚糖，以及微藻提取物及其用途。
• Compounds that modulate fatty acid receptor activity and pet food products containing the same
  申请人：MARS, INCORPORATED

  公开号：US10827772B2

  公开（公告）日：2020-11-10

  A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.

  本文描述了一种风味组合物，该组合物包含至少一种可调节、增加和/或增强 GPR120 脂肪酸受体活性的化合物，可用于增强宠物食品的脂肪酸味道和/或适口性。本文还公开了鉴定所述化合物的方法。