N,N-Diethyl-α-ethoxy-acetamid | 53136-39-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-Diethyl-α-ethoxy-acetamid
• 英文别名: 2-ethoxy-N,N-diethylacetamide
• CAS: 53136-39-3
• 化学式: C₈H₁₇NO₂
• mdl: MFCD03929277
• 分子量: 159.228
• InChiKey: NAHNDIHRYCGHNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.875
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  sodium ethanolate 、 N,N-二乙基-2-氯乙酰胺 以 甲苯 为溶剂， 生成 N,N-Diethyl-α-ethoxy-acetamid
  参考文献：
  名称：

  The Darzens Condensation. I. Reaction of Chloroacetamides with Acetone and Cyclohexanone

  摘要：

  DOI：

  10.1021/jo01067a034

文献信息

• RENIN INHIBITORS
  申请人：Jones Benjamin

  公开号：US20100210635A1

  公开（公告）日：2010-08-19

  Compounds, pharmaceutical compositions, kits and methods are provided for use with Renin that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

  提供了用于与Renin一起使用的化合物、药物组合物、试剂盒和方法，其中包括从以下组中选择的化合物：其中变量如本文所定义。
• Renin inhibitors
  申请人：Jones Benjamin

  公开号：US20090105251A1

  公开（公告）日：2009-04-23

  Compounds, pharmaceutical compositions, kits and methods are provided for use with renin that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

  提供了与肾素一起使用的化合物、药物组合物、试剂盒和方法，其中包括从以下组中选择的化合物：其中变量如本文所定义。
• Modulators of muscarinic receptors
  申请人：Davies Robert

  公开号：US20070213315A1

  公开（公告）日：2007-09-13

  The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

  本发明涉及毒蕈碱受体调节剂。本发明还提供包含此类调节剂的组合物，并使用这些方法治疗毒蕈碱受体介导的疾病。
• Modulators of Muscarinic Receptors
  申请人：Davies Robert

  公开号：US20120196857A9

  公开（公告）日：2012-08-02

  The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

  本发明涉及毒蕈碱受体的调节剂。本发明还提供包含这种调节剂的组合物，并且提供了使用这些组合物治疗毒蕈碱受体介导疾病的方法。
• WATER-REPELLING, OIL-REPELLING AGENT COMPOSITION, METHOD FOR PRODUCING SAME, AND ARTICLE
  申请人：Asahi Glass Company, Limited

  公开号：EP2703465A1

  公开（公告）日：2014-03-05

  To provide a water/oil repellent composition which can produce an article which has favorable water/oil repellency and washing durability, into which infiltration of a coating liquid to form a moisture-permeable waterproofing film or the like can be suppressed and which is excellent in the design, and which presents a low environmental impact, its production method and an article having its surface treated with the water/oil repellent composition. A water/oil repellent composition comprising a polymer having structural units based on the following monomer (a) and structural units based on the following monomer (b), and an aqueous medium containing water and the following amide solvent (I) is used. Monomer (a): a compound represented by (Z-Y)nX, wherein Z is a C1-6 polyfluoroalkyl group or the like, Y is a bivalent organic group having no fluorine atom or the like, n is 1 or 2, and X is a polymerizable unsaturated group. Monomer (b): vinyl chloride. Amide solvent (I): a compound represented by R1O(CH2)r(CHR4)sC(O)NR2R3, wherein r is an integer of from 0 to 3, s is 0 or 1, R1 is a C1-3 alkyl group, each of R2 and R3 is a methyl group or the like, and R4 is a hydrogen atom or the like.

  本发明旨在提供一种防水/防油组合物，该组合物可生产出具有良好防水/防油性能和耐洗涤性的物品，可抑制涂料液渗入该物品以形成透湿防水膜或类似物，该物品设计优良，对环境的影响较小，并提供其生产方法和使用该防水/防油组合物对其表面进行处理的物品。 一种防水/防油组合物，包括具有基于以下单体 (a) 的结构单元和基于以下单体 (b) 的结构单元的聚合物，以及含有水和以下酰胺溶剂 (I) 的水介质。单体 (a)：由 (Z-Y)nX 表示的化合物，其中 Z 是 C1-6 多氟烷基或类似基团，Y 是不含氟原子的二价有机基团或类似基团，n 是 1 或 2，X 是可聚合的不饱和基团。单体 (b)：氯乙烯。酰胺溶剂 (I)：由 R1O(CH2)r(CHR4)sC(O)NR2R3 表示的化合物，其中 r 是 0 至 3 的整数，s 是 0 或 1，R1 是 C1-3 烷基，R2 和 R3 各为甲基或类似基团，R4 是氢原子或类似基团。