The present invention generally relates to implantable devices for producing insulin in diabetic animals and to methods of making same. Some embodiments include amphiphilic biomembranes for use in biological applications (e.g., as an alternative and/or supplemental insulin source). Some embodiments also include live insulin-producing cells contained within one or more amphiphilic membranes so as to prevent or diminish an immuno-response and/or rejection by the host.
本发明通常涉及用于在糖尿病动物中产生
胰岛素的可植入设备以及制造方法。一些实施例包括用于
生物应用的两亲性
生物膜(例如,作为替代和/或补充
胰岛素来源)。一些实施例还包括包含在一个或多个两亲性膜内的活性
胰岛素产生细胞,以防止或减轻宿主的免疫反应和/或排斥反应。