4-[[3,5-Bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-undec-10-enoxyspiro[2-benzofuran-3,4'-piperidine]-1-one | 1193085-98-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[[3,5-Bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-undec-10-enoxyspiro[2-benzofuran-3,4'-piperidine]-1-one
• 英文别名: 4-[[3,5-bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-undec-10-enoxyspiro[2-benzofuran-3,4'-piperidine]-1-one
• CAS: 1193085-98-1
• 化学式: C₄₉H₆₁N₃O₃
• 分子量: 740.042
• InChiKey: AVKNRRVNKICBSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.7
• 重原子数：
  55
• 可旋转键数：
  16
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  63.5
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  二甲基一氯硅烷 、 4-[[3,5-Bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-undec-10-enoxyspiro[2-benzofuran-3,4'-piperidine]-1-one 在 铂(0)-1,3-二乙烯-1,1,3,3-四甲基二硅氧烷 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 、 二氯甲烷 为溶剂， 反应 18.42h， 生成 4-[[3,5-Bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-[11-[chloro(dimethyl)silyl]undecoxy]spiro[2-benzofuran-3,4'-piperidine]-1-one
  参考文献：
  名称：

  Immobilization of a Photoswitchable Piperidine Base

  摘要：

  The synthesis of a photoswitchable piperidine base, carrying a monochlorosilane anchoring group, and its immobilization on silica gel, mimicking an oxide surface, is reported. Efficient photoswitching between the E and Z isomers of the azobenzene photochrome was demonstrated for the immobilization precursor in solution and the immobilized piperidine base in suspension of the functionalized silica gel.

  DOI：

  10.1021/ol902166a
• 作为产物：
  描述：

  在 copper(l) iodide 、 caesium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 以15%的产率得到4-[[3,5-Bis(2,6-dimethylphenyl)phenyl]diazenyl]-1'-tert-butyl-7-undec-10-enoxyspiro[2-benzofuran-3,4'-piperidine]-1-one
  参考文献：
  名称：

  Immobilization of a Photoswitchable Piperidine Base

  摘要：

  The synthesis of a photoswitchable piperidine base, carrying a monochlorosilane anchoring group, and its immobilization on silica gel, mimicking an oxide surface, is reported. Efficient photoswitching between the E and Z isomers of the azobenzene photochrome was demonstrated for the immobilization precursor in solution and the immobilized piperidine base in suspension of the functionalized silica gel.

  DOI：

  10.1021/ol902166a

文献信息

• Immobilization of a Photoswitchable Piperidine Base
  作者：Ragnar S. Stoll、Stefan Hecht

  DOI：10.1021/ol902166a

  日期：2009.11.5

  The synthesis of a photoswitchable piperidine base, carrying a monochlorosilane anchoring group, and its immobilization on silica gel, mimicking an oxide surface, is reported. Efficient photoswitching between the E and Z isomers of the azobenzene photochrome was demonstrated for the immobilization precursor in solution and the immobilized piperidine base in suspension of the functionalized silica gel.