p-Tolyl-chlorbrommethyl-sulfon | 195371-23-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-Tolyl-chlorbrommethyl-sulfon
• 英文别名: [Bromo(chloro)methyl]sulfonylbenzene
• CAS: 195371-23-4
• 化学式: C₇H₆BrClO₂S
• 分子量: 269.546
• InChiKey: VQYLCBZKBIEIPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  p-Tolyl-chlorbrommethyl-sulfon 在 sodium tetrahydroborate 、 二苯基二硒醚 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 以99%的产率得到氯甲基苯砜
  参考文献：
  名称：

  A simple reduction of α-bromosulfones by

  摘要：

  Reduction of alpha-bromosulfones 1, 5, 13-16 by cat.(PhSe)(2)/NaBH4 occurred site-selectively in high yields. This reduction of 1,3- or 1,4-dibromobis(sulfone) 21 and 25 was applied to intramolecular coupling reactions to give the three- and four-membered carbocycles 26-28. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01230-6
• 作为产物：
  描述：

  2-(苯基磺酰)苯乙酮 在 sodium hydroxide 、 potassium chloride 、 双氧水 、 溴 、 三乙胺 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 反应 18.5h， 生成 p-Tolyl-chlorbrommethyl-sulfon
  参考文献：
  名称：

  Chemoselective mono halogenation of β-keto-sulfones using potassium halide and hydrogen peroxide; synthesis of halomethyl sulfones and dihalomethyl sulfones

  摘要：

  The synthesis of alpha-halo beta-keto-sulfones using potassium halide and hydrogen peroxide as a chemoselective mono halogenation reagent and the synthesis of alpha, alpha-symmetrical and asymmetrical dihalo beta-keto-sulfones and alpha-halo, alpha-alkyl and beta-keto-sulfones is described. Base induced cleavage of alpha-halo beta-keto-sulfones, alpha,alpha-dihalo beta-keto-sulfones, and alpha-halo, alpha-alkyl beta-keto-sulfones afforded the corresponding halomethyl sulfones, dihalomethyl sulfones and haloalkyl sulfones. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.11.129

文献信息

• 2,4,6-Phenyl substituted cyclic ketoenols
  申请人：Fischer Reiner

  公开号：US20070015664A1

  公开（公告）日：2007-01-18

  The present invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I) in which W, X, Y and CKE have the meanings given in the disclosure, to a plurality of processes for their preparation and to their use as pesticides and/or herbicides. The invention further relates to selectively herbicidal compositions containing 2,4,6-phenyl-substituted cyclic ketoenols and a compound which improves crop plant tolerance.
• Selective Insecticides and/or Acaricides Based on Substituted Cyclic Dicarbonyl Compounds and Safeners
  申请人：Fischer Reiner

  公开号：US20080200499A1

  公开（公告）日：2008-08-21

  The present invention relates to the use of selective insecticidal and/or acaricidal compositions, characterized in that they comprise an effective amount of an active compound combination comprising (a) at least one substituted cyclic dicarbonyl compound of the formula (I) in which W, X, Y and Z are as defined in the description and CDC is one of the dicarbonyl radicals mentioned in the description, and (b) at least one crop plant compatibility-improving compound from the group of compounds given in the description. for controlling insects and/or arachnids, and also to a method for controlling insects and/or arachnids using the compositions.
• US7888285B2
  申请人：——

  公开号：US7888285B2

  公开（公告）日：2011-02-15
• Chemoselective mono halogenation of β-keto-sulfones using potassium halide and hydrogen peroxide; synthesis of halomethyl sulfones and dihalomethyl sulfones
  作者：N. Suryakiran、P. Prabhakar、T. Srikanth Reddy、K. Chinni Mahesh、K. Rajesh、Y. Venkateswarlu

  DOI：10.1016/j.tetlet.2006.11.129

  日期：2007.1

  The synthesis of alpha-halo beta-keto-sulfones using potassium halide and hydrogen peroxide as a chemoselective mono halogenation reagent and the synthesis of alpha, alpha-symmetrical and asymmetrical dihalo beta-keto-sulfones and alpha-halo, alpha-alkyl and beta-keto-sulfones is described. Base induced cleavage of alpha-halo beta-keto-sulfones, alpha,alpha-dihalo beta-keto-sulfones, and alpha-halo, alpha-alkyl beta-keto-sulfones afforded the corresponding halomethyl sulfones, dihalomethyl sulfones and haloalkyl sulfones. (c) 2006 Elsevier Ltd. All rights reserved.
• A simple reduction of α-bromosulfones by
  作者：Mitsuhiro Yoshimatsu、Megumi Ohara

  DOI：10.1016/s0040-4039(97)01230-6

  日期：1997.8

  Reduction of alpha-bromosulfones 1, 5, 13-16 by cat.(PhSe)(2)/NaBH4 occurred site-selectively in high yields. This reduction of 1,3- or 1,4-dibromobis(sulfone) 21 and 25 was applied to intramolecular coupling reactions to give the three- and four-membered carbocycles 26-28. (C) 1997 Elsevier Science Ltd.