2-((2-(((dodecylthio)carbonothioyl)thio)-2-methylpropanoyl)oxy)ethyl acrylate | 1360152-51-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-((2-(((dodecylthio)carbonothioyl)thio)-2-methylpropanoyl)oxy)ethyl acrylate
• 英文别名: 2-Prop-2-enoyloxyethyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate；2-prop-2-enoyloxyethyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
• CAS: 1360152-51-7
• 化学式: C₂₂H₃₈O₄S₃
• 分子量: 462.739
• InChiKey: RXZOIAALLOUTDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  29
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  135
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-[十二烷硫基(硫代羰基)硫基]-2-甲基丙酸 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 生成 2-((2-(((dodecylthio)carbonothioyl)thio)-2-methylpropanoyl)oxy)ethyl acrylate
  参考文献：
  名称：

  水溶性和可点击的分段超支化聚合物，用于多功能化和新型体系结构的构建

  摘要：

  通过自缩性乙烯基共聚（SCVCP）和可逆加成-断裂链转移相结合，合成了一系列具有亲水核和疏水壳的新型且窄分散的规则链节超支化聚甲基丙烯酸叔丁酯（HPTAM）。 （RAFT）方法论。在各种摩尔进料比（γ，[DMAEMA]： [ACDT]）被选作结构线性链段形成的单体。共聚动力学表明，在聚合过程中，实时γ值几乎保持恒定，并且与初始进料比一致。因此，HPTAM在每两个相邻的分支单元之间拥有规则的线性链，在结构上与HyperMacs非常相似。分段的超支化聚合物与炔丙基溴和2-叠氮基乙基2-溴乙酸酯的快速点击样Menschutkin反应（即季铵化）易于制得水溶性且可点击的聚（甲基丙烯酸炔丙基季铵盐）（HPPrAM）和聚（叠氮化物）甲基丙烯酸季铵盐）（HPAzAM）。通过Cu（I）催化的叠氮化物-炔烃环加成反应（CuAAC），HPPrAMs分别用1-叠氮十二烷和2-叠氮乙基2-溴异丁酸酯官能化，从而产

  DOI：

  10.1021/ma300718d

文献信息

• IMPROVED POPPET FOR CRYOGENIC FLUID COUPLING
  申请人：JC CARTER LLC

  公开号：US20170129970A1

  公开（公告）日：2017-05-11

  Subject polymers have a plurality of repeating units having amino-bis-phosphonate functionality pendent groups of a polyacrylate, polymethacrylate, polyacrylamide, polymethacrylamide, or linear polyethyleneimine. The polymers are prepared from a plurality of monomers comprising amino-te-phosphonate functionality or from a polymer having NHBoc or active ester pendent groups that are subsequently transformed into the amino-bis-phosphonate comprising polymer. The amino-bis-phosphonate comprising polymers or their precursor polymers can be prepared by RAFT polymerization or by transformation of a preformed polymer. The amino-bis-phosphonate comprising polymers can be linear or branched polymers. The amino-bis-phosphonate comprising polymers can be complexed with metal ions. The metal ions can be a radionuclide and the amino-bis-phosphonate comprising polymer complexes can be used as radiotherapeutic agents.
• [EN] AMINO-BIS-PHOSPHONATE-CONTAINING POLYMERS VIA RAFT POLYMERIZATION AND BASED ON LINEAR POLYETHYLENEIMINE<br/>[FR] POLYMÈRES CONTENANT UN AMINO-BIS-PHOSPHONATE PAR L'INTERMÉDIAIRE DE POLYMÉRISATION RAFT ET SUR BASE DE POLYÉTHYLÈNEIMINE LINÉAIRE
  申请人：UNIV FLORIDA

  公开号：WO2015138566A1

  公开（公告）日：2015-09-17

  Subject polymers have a plurality of repeating units having amino-bis-phosphonate functionality pendent groups of a polyacrylate, polymethacrylate, polyacrylamide, polymethacrylamide, or linear polyethyleneimine. The polymers are prepared from a plurality of monomers comprising amino-te-phosphonate functionality or from a polymer having NHBoc or active ester pendent groups that are subsequently transformed into the amino-bis-phosphonate comprising polymer. The amino-bis-phosphonate comprising polymers or their precursor polymers can be prepared by RAFT polymerization or by transformation of a preformed polymer. The amino-bis-phosphonate comprising polymers can be linear or branched polymers. The amino-bis-phosphonate comprising polymers can be complexed with metal ions. The metal ions can be a radionuclide and the amino-bis-hosphonate comprising polymer complexes can be used as radiotherapeutic agents.