4-(2-chloroethyl)carboxyl-N-hydroxyphthalimide | 887704-64-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4-(2-chloroethyl)carboxyl-N-hydroxyphthalimide
• 英文别名: 2-Chloroethyl 2-hydroxy-1,3-dioxoisoindole-5-carboxylate；2-chloroethyl 2-hydroxy-1,3-dioxoisoindole-5-carboxylate
• CAS: 887704-64-5
• 化学式: C₁₁H₈ClNO₅
• 分子量: 269.641
• InChiKey: PKWZPKQTQSFTOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  83.9
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(2-chloroethyl)carboxyl-N-hydroxyphthalimide 、 N-甲基咪唑 以 甲苯 为溶剂， 反应 2.0h， 以100%的产率得到4-(2-chloroethyl)carboxyl-N-hydroxyphthalimide 3-methyl-1H-imidazol-1-ium chloride
  参考文献：
  名称：

  Synthetic utilities of ionic liquid-supported NHPI complex

  摘要：

  Ionic liquid (IL)-supported NHPI complex for the oxidation and/or nitration was prepared. Synthetic utilities of the complex as recoverable and recyclable system in ionic liquid were described. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.02.077
• 作为产物：
  描述：

  2-Benzyloxy-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carbonyl chloride 在 吡啶 、 三氯化铁 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 生成 4-(2-chloroethyl)carboxyl-N-hydroxyphthalimide
  参考文献：
  名称：

  Synthetic utilities of ionic liquid-supported NHPI complex

  摘要：

  Ionic liquid (IL)-supported NHPI complex for the oxidation and/or nitration was prepared. Synthetic utilities of the complex as recoverable and recyclable system in ionic liquid were described. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.02.077

文献信息

• Synthetic utilities of ionic liquid-supported NHPI complex
  作者：Shinichi Koguchi、Tomoya Kitazume

  DOI：10.1016/j.tetlet.2006.02.077

  日期：2006.4

  Ionic liquid (IL)-supported NHPI complex for the oxidation and/or nitration was prepared. Synthetic utilities of the complex as recoverable and recyclable system in ionic liquid were described. (c) 2006 Elsevier Ltd. All rights reserved.