4-[N-(4-甲酰基苯基)氨基]苯甲醛 | 336619-72-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-[N-(4-甲酰基苯基)氨基]苯甲醛
• 英文名称: 4-[N-(4-formylphenyl)amino]benzaldehyde
• 英文别名: 4,4'-Diformyldiphenylamine；4-(4-formylanilino)benzaldehyde
• CAS: 336619-72-8
• 化学式: C₁₄H₁₁NO₂
• 分子量: 225.247
• InChiKey: KJDQBASWKQBLGP-UHFFFAOYSA-N

物化性质

• 沸点：
  425.2±30.0 °C(Predicted)
• 密度：
  1.259±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-[N-(4-甲酰基苯基)氨基]苯甲醛 、 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  Use of aggregation-induced emission compounds in dispersion detecting of nanoparticles

  摘要：

  提供了一种聚集诱导发光化合物在纳米颗粒的分散检测中的应用。纳米颗粒的分散检测包括将聚集诱导发光化合物修饰在纳米颗粒表面上，以获得修饰后的纳米颗粒溶液。纳米颗粒的分散检测包括激发修饰后的纳米颗粒溶液，并通过溶液的发光状态来确定纳米颗粒的分散程度。

  公开号：

  US10392342B1
• 作为产物：
  描述：

  4-[N-allyl-N-(4-formylphenyl)amino]benzaldehyde 在 palladium on activated charcoal 甲烷磺酸 作用下， 以 乙醇 为溶剂， 以25%的产率得到4-[N-(4-甲酰基苯基)氨基]苯甲醛
  参考文献：
  名称：

  Synthetic Strategies to Derivatizable Triphenylamines Displaying High Two-Photon Absorption

  摘要：

  [Graphics]A versatile synthetic strategy to access a set of highly fluorescent g-conjugated triphenylamines bearing a functional linker at various positions on one phenyl ring is described. These compounds were designed for large two-photon absorption (2PA) and in particular for labeling of biomolecules. The monoderivatized trisformylated or trisiodinated intermediates described herein allow introduction of a large variety of electron-withdrawing groups required for large 2PA as well as a panel of chemical functions suitable for coupling to biomolecules. The monoderivatized three-branched compounds and in particular the benzothiazole JP-3Bz) series show remarkable linear (high extinction coefficients and high quantum yield) and nonlinear (high 2-photon cross sections) optical properties. Interestingly the presence of functional side chains does not disturb the two-photon absorption. Finally, monoderivatized two-branched derivatives also appear to be valuable candidates. Altogether the good optical properties of the new derivatizable pi-conjugated TPA combined with their small size and their compatibility with bioconjugation protocols suggest that they represent a new chemical class of labels potentially applicable for the tracking of biomolecules using two-photon scanning microscopy.

  DOI：

  10.1021/jo702002y

文献信息

• Optimization of the central linker of dicationic bis-benzimidazole anti-MRSA and anti-VRE agents
  作者：Laixing Hu、Maureen L. Kully、David W. Boykin、Norman Abood

  DOI：10.1016/j.bmcl.2009.05.061

  日期：2009.7

  A series of bis-benzimidazole diamidine compounds containing different central linkers has been synthesized and evaluated for in vitro antibacterial activities, including drug-resistant bacterial strains. Seven compounds have shown potent antibacterial activities. The anti-MRSA and anti-VRE activities of compound 1h were more potent than that of the lead compound 1a and vancomycin. (C) 2009 Elsevier Ltd. All rights reserved.
• US3948861A
  申请人：——

  公开号：US3948861A

  公开（公告）日：1976-04-06
• [EN] TELOMERASE INHIBITOR<br/>[FR] INHIBITEUR DE TELOMERASE
  申请人：GERON CORP

  公开号：WO2002053155A1

  公开（公告）日：2002-07-11

  The present invention provides a telomerase inhibitor containing as an active ingredient a compound which has the 4-oxo-2-thioxoimidazolidine skeleton and which has telomerase inhibitory activity.
• COMPOUNDS AND APPLICATIONS THEREOF IN FIELD OF OPTOELECTRONICS
  申请人：Zhejiang Brilliant Optoelectronic Technology Co.,Ltd.

  公开号：US20240043413A1

  公开（公告）日：2024-02-08

  Provided are compounds including a structural unit of one of formulas (1)-(4). Also provided are formulations containing the compounds, at least one organic solvent, and/or the organic resins. Further provided are organic light-emitting devices containing the compounds.
• Synthetic Strategies to Derivatizable Triphenylamines Displaying High Two-Photon Absorption
  作者：Rémy Lartia、Clémence Allain、Guillaume Bordeau、Falk Schmidt、Céline Fiorini-Debuisschert、Fabrice Charra、Marie-Paule Teulade-Fichou

  DOI：10.1021/jo702002y

  日期：2008.3.1

  [Graphics]A versatile synthetic strategy to access a set of highly fluorescent g-conjugated triphenylamines bearing a functional linker at various positions on one phenyl ring is described. These compounds were designed for large two-photon absorption (2PA) and in particular for labeling of biomolecules. The monoderivatized trisformylated or trisiodinated intermediates described herein allow introduction of a large variety of electron-withdrawing groups required for large 2PA as well as a panel of chemical functions suitable for coupling to biomolecules. The monoderivatized three-branched compounds and in particular the benzothiazole JP-3Bz) series show remarkable linear (high extinction coefficients and high quantum yield) and nonlinear (high 2-photon cross sections) optical properties. Interestingly the presence of functional side chains does not disturb the two-photon absorption. Finally, monoderivatized two-branched derivatives also appear to be valuable candidates. Altogether the good optical properties of the new derivatizable pi-conjugated TPA combined with their small size and their compatibility with bioconjugation protocols suggest that they represent a new chemical class of labels potentially applicable for the tracking of biomolecules using two-photon scanning microscopy.