Bis-(2-hydroxy-ethyl)-carbamic acid 2-({2-[2-(bis-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-carbamoyloxy)-ethoxy]-ethoxycarbonyl}-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-amino)-ethyl ester | 275385-35-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Bis-(2-hydroxy-ethyl)-carbamic acid 2-({2-[2-(bis-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-carbamoyloxy)-ethoxy]-ethoxycarbonyl}-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-amino)-ethyl ester
• CAS: 275385-35-8
• 化学式: C₃₄H₆₄N₆O₂₁
• 分子量: 892.91
• InChiKey: PGQGRRVIUVKMKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.43
• 重原子数：
  61.0
• 可旋转键数：
  34.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  348.31
• 氢给体数：
  8.0
• 氢受体数：
  21.0

反应信息

• 作为反应物：
  描述：

  对硝基苯基氯甲酸酯 、 Bis-(2-hydroxy-ethyl)-carbamic acid 2-({2-[2-(bis-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-carbamoyloxy)-ethoxy]-ethoxycarbonyl}-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-amino)-ethyl ester 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 生成 2-[2-[2-[2-[Bis[2-[bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethyl]carbamoyloxy]ethoxy]ethoxycarbonyl-[2-[bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethyl]amino]ethoxycarbonyl-[2-(4-nitrophenoxy)carbonyloxyethyl]amino]ethyl (4-nitrophenyl) carbonate
  参考文献：
  名称：

  Synthesis of multivalent carbonate esters by divergent growth of branched carbamates

  摘要：

  Multivalent 4-nitrophenyl (PNP)-carbonate esters were prepared from carbonate ester-containing core groups by a new divergent-growth process. The process doubles the number of PNP-carbonate esters with each round of growth, or branching, which occurs by reacting an N,N-dihydroxylalkyl amine with a PNP-carbonate ester. The resulting N,N-dihydroxyalkyl carbamate contains two hydroxyl groups for each original PNP-carbonate ester. The hydroxyl groups are converted in situ to PNP-carbonate esters, and the process can be repeated to provide successive generations of dendrimer-like branched structures of increased valence. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(01)00078-8
• 作为产物：
  描述：

  Bis-(2-hydroxy-ethyl)-carbamic acid 2-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethoxy}-ethyl ester 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 25.0h， 生成 Bis-(2-hydroxy-ethyl)-carbamic acid 2-({2-[2-(bis-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-carbamoyloxy)-ethoxy]-ethoxycarbonyl}-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-amino)-ethyl ester
  参考文献：
  名称：

  Synthesis of multivalent carbonate esters by divergent growth of branched carbamates

  摘要：

  Multivalent 4-nitrophenyl (PNP)-carbonate esters were prepared from carbonate ester-containing core groups by a new divergent-growth process. The process doubles the number of PNP-carbonate esters with each round of growth, or branching, which occurs by reacting an N,N-dihydroxylalkyl amine with a PNP-carbonate ester. The resulting N,N-dihydroxyalkyl carbamate contains two hydroxyl groups for each original PNP-carbonate ester. The hydroxyl groups are converted in situ to PNP-carbonate esters, and the process can be repeated to provide successive generations of dendrimer-like branched structures of increased valence. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(01)00078-8