ethyl 3-{4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrazol-5-yl}propanoate | 796845-67-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-{4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrazol-5-yl}propanoate
• 英文别名: Ethyl 3-[2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]pyrazol-3-yl]propanoate
• CAS: 796845-67-5
• 化学式: C₁₄H₂₃N₃O₄
• 分子量: 297.354
• InChiKey: RGLSSIGLPIIYJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  82.4
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] CEPHEM COMPOUNDS<br/>[FR] COMPOSES CEPHEMES
  申请人：FUJISAWA PHARMACEUTICAL CO

  公开号：WO2004101571A1

  公开（公告）日：2004-11-25

  The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl which may have suitable substituent(s), R2 is amino, protected amino or guanidino, R3 is carboxy or protected carboxy, R4 is amino or protected amino, and A is lower alkylene, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.

  本发明涉及一种化合物，其化学式为[I]：其中R1是可能具有适当取代基的低碳烷基，R2是氨基、保护氨基或胍基，R3是羧基或保护羧基，R4是氨基或保护氨基，A是低碳烷基，或其在药学上可接受的盐，一种制备化合物[I]的方法，以及包含化合物[I]与药学上可接受的载体混合的药物组合物。
• Cephem compounds
  申请人：Yamanaka Toshio

  公开号：US20050004094A1

  公开（公告）日：2005-01-06

  The present invention relates to a compound of the formula [I]: wherein R 1 is lower alkyl which may have suitable substituent(s), R 2 is amino, protected amino or guanidino, R 3 is carboxy or protected carboxy, R 4 is amino or protected amino, and A is lower alkylene, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.

  本发明涉及一种化合物，其化学式为[I]，其中R1是较低的烷基，可以具有适当的取代基；R2是氨基，保护氨基或鸟氨酸基；R3是羧基或保护羧基；R4是氨基或保护氨基，A是较低的烷基烯，或其药学上可接受的盐，以及制备化合物[I]的方法和包含化合物[I]的药物组合物与药学上可接受的载体混合的药物组合物。