G2-(OH)₈ | 497147-15-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: G2-(OH)₈
• 英文别名: 2-[[3-[4-[3-[Bis[2-[3-[bis(2-hydroxyethyl)amino]propanoyloxy]ethyl]amino]propanoyl]piperazin-1-yl]-3-oxopropyl]-[2-[3-[bis(2-hydroxyethyl)amino]propanoyloxy]ethyl]amino]ethyl 3-[bis(2-hydroxyethyl)amino]propanoate；2-[[3-[4-[3-[bis[2-[3-[bis(2-hydroxyethyl)amino]propanoyloxy]ethyl]amino]propanoyl]piperazin-1-yl]-3-oxopropyl]-[2-[3-[bis(2-hydroxyethyl)amino]propanoyloxy]ethyl]amino]ethyl 3-[bis(2-hydroxyethyl)amino]propanoate
• CAS: 497147-15-6
• 化学式: C₄₆H₈₈N₈O₁₈
• 分子量: 1041.25
• InChiKey: MFMUWRRXBVPNKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.1
• 重原子数：
  72
• 可旋转键数：
  50
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  327
• 氢给体数：
  8
• 氢受体数：
  24

反应信息

• 作为反应物：
  描述：

  丙烯酰氯 、 G2-(OH)₈ 以 二氯甲烷 、 三乙胺 为溶剂， 反应 13.0h， 以62%的产率得到G2-(acrylate)₈
  参考文献：
  名称：

  A divergent synthesis of new aliphatic poly(ester-amine) dendrimers bearing peripheral hydroxyl or acrylate groups

  摘要：

  A novel class of aliphatic poly(ester-amine) dendrimers, bearing hydroxyl or acrylate peripheral groups, was designed and synthesized via a divergent strategy using readily available piperazine, diethanolamine and acryloyl chloride as the monomeric building blocks. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)02329-8
• 作为产物：
  描述：

  G1-(OH)₄ 以 乙醇 、 二氯甲烷 、 三乙胺 为溶剂， 反应 33.0h， 生成 G2-(OH)₈
  参考文献：
  名称：

  A divergent synthesis of new aliphatic poly(ester-amine) dendrimers bearing peripheral hydroxyl or acrylate groups

  摘要：

  A novel class of aliphatic poly(ester-amine) dendrimers, bearing hydroxyl or acrylate peripheral groups, was designed and synthesized via a divergent strategy using readily available piperazine, diethanolamine and acryloyl chloride as the monomeric building blocks. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)02329-8

文献信息

• A divergent synthesis of new aliphatic poly(ester-amine) dendrimers bearing peripheral hydroxyl or acrylate groups
  作者：Yaowu Sha、Liang Shen、Xiaoyin Hong

  DOI：10.1016/s0040-4039(02)02329-8

  日期：2002.12

  A novel class of aliphatic poly(ester-amine) dendrimers, bearing hydroxyl or acrylate peripheral groups, was designed and synthesized via a divergent strategy using readily available piperazine, diethanolamine and acryloyl chloride as the monomeric building blocks. (C) 2002 Elsevier Science Ltd. All rights reserved.